Lead poisoning among asymptomatic individuals with a long-term history of opiate use in Golestan Cohort Study

Recent reports of lead poisoning suggest that people who use opium may be exposed to high amounts of lead. Here, we investigate the association between opium use and blood lead levels (BLL) in a population-based cohort study. In 2017, we studied a random sample of 410 people who currently (both with...

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Bibliographic Details
Published in:The International journal of drug policy 2022-06, Vol.104, p.103695-103695, Article 103695
Main Authors: Etemadi, Arash, Hariri, Sanam, Hassanian-moghaddam, Hossein, Poustchi, Hossein, Roshandel, Gholamreza, Shayanrad, Amaneh, Kamangar, Farin, Boffetta, Paolo, Brennan, Paul, Dargan, Paul I., Dawsey, Sanford M., Jones, Robert L., Freedman, Neal D., Malekzadeh, Reza, Abnet, Christian C.
Format: Article
Language:English
Subjects:
Analgesics, Opioid
Blood lead level
Cancer
Cohort analysis
Cohort Studies
Drug policy
Humans
Lead
Lead content
Lead Poisoning
Narcotics
Opiate Alkaloids
Opiates
Opioids
Opium
Opium Dependence - epidemiology
Residence
Smoking
Spectrometry
Tobacco
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Summary:Recent reports of lead poisoning suggest that people who use opium may be exposed to high amounts of lead. Here, we investigate the association between opium use and blood lead levels (BLL) in a population-based cohort study. In 2017, we studied a random sample of 410 people who currently (both within the past year and the past month) used opium and 104 who did not from participants of the Golestan Cohort Study in northeast Iran. Participants were stratified by sex and tobacco use history, completed a comprehensive opiate and tobacco use questionnaire and provided blood. BLL was measured by Lead Care® II Blood Lead Test Kit, validated by inductively coupled plasma triple quadrupole mass spectrometry. BLL was categorized as “
ISSN:0955-3959
1873-4758
DOI:10.1016/j.drugpo.2022.103695