Age modifies both the maximal temperature and inflammatory response in patients with SARS-CoV-2 infection

To determine the maximal response of the temperature and inflammatory response to SARS-CoV-2 infection and how these are modified by age. Participants were patients admitted to hospital with SARS-CoV-2 infection. For each participant, the maximal temperature and serum C-reactive protein (CRP) were i...

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Bibliographic Details
Published in:Clinical medicine (London, England) England), 2022-05, Vol.22 (3), p.192-196
Main Authors: Crooks, Colin J, West, Joe, Morling, Joanne R, Simmonds, Mark, Juurlink, Irene, Briggs, Steve, Cruickshank, Simon, Hammond-Pears, Susan, Shaw, Dominick, Card, Timothy R, Fogarty, Andrew
Format: Article
Language:English
Subjects:
age
Age groups
Blood pressure
Confidence intervals
Coronaviruses
COVID-19
Disease
Hospitals
Hypotheses
infection
Infections
inflammation
Neutrophils
Original Research
Patients
Physiology
Pneumonia
Proteins
Severe acute respiratory syndrome coronavirus 2
Steroids
temperature
Viral infections
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Summary:To determine the maximal response of the temperature and inflammatory response to SARS-CoV-2 infection and how these are modified by age. Participants were patients admitted to hospital with SARS-CoV-2 infection. For each participant, the maximal temperature and serum C-reactive protein (CRP) were identified and stratified by age. In a secondary analysis, these were compared in patients treated before and after dexamethasone. Mean maximal temperature varied by age (p
ISSN:1470-2118
1473-4893
DOI:10.7861/clinmed.2021-0603