Primary peritoneal high-grade serous carcinoma in a man: A case report

• Published in: Annals of medicine and surgery 2022-05, Vol.77, p.103605, Article 103605
• Main Authors: Guellil, Abdelali, Jabi, Rachid, Mabrouk, Mohamed Yassine, Bouzayan, Laila, Merhoum, Abdelali, Del Gallo, Gérald, Godart, Claire, Bouziane, Mohammed
• Format: Article
• Language: English
• Subjects: Case Report; Diagnosis; High-grade primary peritoneal serous carcinoma; Histology; Male
• ISSN: 2049-0801; 2049-0801
• DOI: 10.1016/j.amsu.2022.103605

Primary peritoneal serous carcinomas (PPSC) are exceedingly rare in male patients. Only a few cases were reported in the medical literature, it's diagnosis is difficult before surgery. In this article, we describe the case of a patient who presented a high-grade primary peritoneal carcinoma, the diagnosis was suspected radiologically following an abdominopelvic computed tomography (CT).the patient underwent exploratory laparoscopic surgery with biopsy of several peritoneal nodules. Pathologic analysis of specimen confirmed the diagnosis of Primary peritoneal serous carcinomas. The patient died one month after his diagnosis while undergoing chemotherapy and palliative care. PPSC is an inoperable malignancy, histology staining confirms the diagnosis, the chemotherapy and palliative care are the only offered treatment. The evolution of the disease is very dark with a poor prognosis. We highlight the important of testicular examination to predict apparition of PPSC in the future. •Primary carcinoma of the peritoneum of high grade is a rare entity.•Surgical exploration with peritoneal biopsy helps in the diagnosis.•Immuno-histochemical analysis and molecular analysis are the gold standard of the diagnosis of this rare entity.•Early chemotherapy is the first-line treatment.•The median survival time of primary peritoneal carcinoma is 1–3 months, which means a poor prognosis.