The role of exclusive breastfeeding on sIgA and lactoferrin levels in toddlers suffering from Acute Respiratory Infection: A cross-sectional study

• Published in: Annals of medicine and surgery 2022-05, Vol.77, p.103644-103644, Article 103644
• Main Authors: Fatimah, Massi, Muhammad Nasrum, Febriani, Andi Dwi Bahagia, Hatta, Mochammad, Karuniawati, Anis, Rauf, Syahrul, Wahyuni, Sitti, Hamid, Firdaus, Alasiry, Ema, Patellongi, Ilham, Permatasari, Tria Astika Endah, Farsida
• Format: Article
• Language: English
• Subjects: Acute respiratory infection (ARI); Cross-sectional Study; Exclusive breastfeeding; Immunization; Lactoferrin; sIgA
• ISSN: 2049-0801; 2049-0801
• DOI: 10.1016/j.amsu.2022.103644

Secretion of Immunoglobulin A (sIgA) and lactoferrin is a nutrient content in breast milk that can increase immunity in preventing infectious diseases such as Acute Respiratory Infection (ARI). This research aims to determine the role of exclusive breastfeeding (EBF) on sIgA and Lactoferrin levels in toddlers suffering from ARI. A cross-sectional study was conducted on 124 toddlers under five from January–July 2021. Toddlers were selected using a purposive technique sampling from three Community Health Centers in Central Jakarta. Data were analyzed using t-test and ANOVA. The history of immunization, EBF, and frequency of ARI was significantly associated with levels of sIgA and lactoferrin. Parity only correlated with sIgA but not with lactoferrin levels. Maternal and toddlers' age, gender, and nutritional status were not significantly related to sIgA and lactoferrin levels. There is a significant (p-value