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Atypical de Winter Presentation of Critical Left Anterior Descending Coronary Artery Occlusion
A 69-year-old male presented with substernal chest pain that started a few hours earlier. On arrival, the patient was hemodynamically stable, and the physical examination was unrevealing. Laboratory workup revealed an elevated high-sensitivity troponin, and an initial electrocardiogram (ECG) reveale...
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Published in: | Curēus (Palo Alto, CA) CA), 2022-05, Vol.14 (5), p.e24724 |
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description | A 69-year-old male presented with substernal chest pain that started a few hours earlier. On arrival, the patient was hemodynamically stable, and the physical examination was unrevealing. Laboratory workup revealed an elevated high-sensitivity troponin, and an initial electrocardiogram (ECG) revealed tall, symmetric T-waves with preceding minor concave ST-segment elevations less than 1 mm in the precordial leads (V1-V6) and 0.5 mm ST elevation in the aVR. Due to concerning ECG changes, the patient was treated for a possible non-ST-segment elevation myocardial infarction. A loading dose of aspirin and clopidogrel was given and a heparin drip was initiated. However, the patient's chest pain persisted requiring multiple sublingual nitroglycerin tablets. Later, on further review of the ECGs, the presence of de Winter T-waves was noted and led to activation of the catheterization laboratory, and an urgent left heart catheterization (LHC) was done. LHC revealed a critical 90% occlusion of the left anterior descending artery, and a drug-eluting stent was placed. The patient had a good recovery thereafter. This case emphasizes the rarity of the case and lack of awareness about the atypical de Winter pattern that is considered to be an ST-segment elevation myocardial infarction equivalent. Failure to recognize this can potentially lead to delayed intervention. |
doi_str_mv | 10.7759/cureus.24724 |
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On arrival, the patient was hemodynamically stable, and the physical examination was unrevealing. Laboratory workup revealed an elevated high-sensitivity troponin, and an initial electrocardiogram (ECG) revealed tall, symmetric T-waves with preceding minor concave ST-segment elevations less than 1 mm in the precordial leads (V1-V6) and 0.5 mm ST elevation in the aVR. Due to concerning ECG changes, the patient was treated for a possible non-ST-segment elevation myocardial infarction. A loading dose of aspirin and clopidogrel was given and a heparin drip was initiated. However, the patient's chest pain persisted requiring multiple sublingual nitroglycerin tablets. Later, on further review of the ECGs, the presence of de Winter T-waves was noted and led to activation of the catheterization laboratory, and an urgent left heart catheterization (LHC) was done. LHC revealed a critical 90% occlusion of the left anterior descending artery, and a drug-eluting stent was placed. The patient had a good recovery thereafter. This case emphasizes the rarity of the case and lack of awareness about the atypical de Winter pattern that is considered to be an ST-segment elevation myocardial infarction equivalent. Failure to recognize this can potentially lead to delayed intervention.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.24724</identifier><identifier>PMID: 35673311</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Acute coronary syndromes ; Angioplasty ; Anticoagulants ; Cardiac arrhythmia ; Cardiac catheterization ; Cardiology ; Cardiovascular disease ; Case reports ; Coronary vessels ; Electrocardiography ; Emergency medical care ; Emergency Medicine ; Heart attacks ; Heart rate ; Internal Medicine ; Intubation ; Laboratories ; Pain ; Patients</subject><ispartof>Curēus (Palo Alto, CA), 2022-05, Vol.14 (5), p.e24724</ispartof><rights>Copyright © 2022, Kainat et al.</rights><rights>Copyright © 2022, Kainat et al. This work is published under https://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2022, Kainat et al. 2022 Kainat et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c266t-b64996bae33dca3cadd425ee7531fee2789fa8fe0089b1a94240d4bb2c544b73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2682639495/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2682639495?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,44590,53791,53793,75126</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35673311$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kainat, Aleesha</creatorcontrib><creatorcontrib>Ain, Noor Ul</creatorcontrib><creatorcontrib>Boricha, Hetal</creatorcontrib><creatorcontrib>Gulzar, Mahdin</creatorcontrib><creatorcontrib>Dueweke, Eric J</creatorcontrib><title>Atypical de Winter Presentation of Critical Left Anterior Descending Coronary Artery Occlusion</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>A 69-year-old male presented with substernal chest pain that started a few hours earlier. On arrival, the patient was hemodynamically stable, and the physical examination was unrevealing. Laboratory workup revealed an elevated high-sensitivity troponin, and an initial electrocardiogram (ECG) revealed tall, symmetric T-waves with preceding minor concave ST-segment elevations less than 1 mm in the precordial leads (V1-V6) and 0.5 mm ST elevation in the aVR. Due to concerning ECG changes, the patient was treated for a possible non-ST-segment elevation myocardial infarction. A loading dose of aspirin and clopidogrel was given and a heparin drip was initiated. However, the patient's chest pain persisted requiring multiple sublingual nitroglycerin tablets. Later, on further review of the ECGs, the presence of de Winter T-waves was noted and led to activation of the catheterization laboratory, and an urgent left heart catheterization (LHC) was done. LHC revealed a critical 90% occlusion of the left anterior descending artery, and a drug-eluting stent was placed. The patient had a good recovery thereafter. This case emphasizes the rarity of the case and lack of awareness about the atypical de Winter pattern that is considered to be an ST-segment elevation myocardial infarction equivalent. Failure to recognize this can potentially lead to delayed intervention.</description><subject>Acute coronary syndromes</subject><subject>Angioplasty</subject><subject>Anticoagulants</subject><subject>Cardiac arrhythmia</subject><subject>Cardiac catheterization</subject><subject>Cardiology</subject><subject>Cardiovascular disease</subject><subject>Case reports</subject><subject>Coronary vessels</subject><subject>Electrocardiography</subject><subject>Emergency medical care</subject><subject>Emergency Medicine</subject><subject>Heart attacks</subject><subject>Heart rate</subject><subject>Internal Medicine</subject><subject>Intubation</subject><subject>Laboratories</subject><subject>Pain</subject><subject>Patients</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><recordid>eNpVkc1LAzEQxYMoKtWbZwl4tZqvTTYXodRPKNSD4M2Qzc7WSLupSVbof-_a1qKnGZjfvHnMQ-iMkiulCn3tughdumJCMbGHjhmV5bCkpdj_0x-h05Q-CCGUKEYUOURHvJCKc0qP0dsor5be2TmuAb_6NkPEzxEStNlmH1ocGjyOPq-RCTQZj34YHyK-heSgrX07w-MQQ2vjCo9iP1zhqXPzLvXrJ-igsfMEp9s6QC_3dy_jx-Fk-vA0Hk2GjkmZh5UUWsvKAue1s9zZuhasAFAFpw0AU6VubNkAIaWuqNWCCVKLqmKuEKJSfIBuNrLLrlpA3dvK0c7NMvpF78oE683_SevfzSx8GU1lUXDeC1xsBWL47CBl8xG62PaWDZMlk1wLXfTU5YZyMaQUodldoMT85GE2eZh1Hj1-_tfVDv79Pv8GliuJsQ</recordid><startdate>20220504</startdate><enddate>20220504</enddate><creator>Kainat, Aleesha</creator><creator>Ain, Noor Ul</creator><creator>Boricha, Hetal</creator><creator>Gulzar, Mahdin</creator><creator>Dueweke, Eric J</creator><general>Cureus Inc</general><general>Cureus</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope></search><sort><creationdate>20220504</creationdate><title>Atypical de Winter Presentation of Critical Left Anterior Descending Coronary Artery Occlusion</title><author>Kainat, Aleesha ; Ain, Noor Ul ; Boricha, Hetal ; Gulzar, Mahdin ; Dueweke, Eric J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c266t-b64996bae33dca3cadd425ee7531fee2789fa8fe0089b1a94240d4bb2c544b73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Acute coronary syndromes</topic><topic>Angioplasty</topic><topic>Anticoagulants</topic><topic>Cardiac arrhythmia</topic><topic>Cardiac catheterization</topic><topic>Cardiology</topic><topic>Cardiovascular disease</topic><topic>Case reports</topic><topic>Coronary vessels</topic><topic>Electrocardiography</topic><topic>Emergency medical care</topic><topic>Emergency Medicine</topic><topic>Heart attacks</topic><topic>Heart rate</topic><topic>Internal Medicine</topic><topic>Intubation</topic><topic>Laboratories</topic><topic>Pain</topic><topic>Patients</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kainat, Aleesha</creatorcontrib><creatorcontrib>Ain, Noor Ul</creatorcontrib><creatorcontrib>Boricha, Hetal</creatorcontrib><creatorcontrib>Gulzar, Mahdin</creatorcontrib><creatorcontrib>Dueweke, Eric J</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kainat, Aleesha</au><au>Ain, Noor Ul</au><au>Boricha, Hetal</au><au>Gulzar, Mahdin</au><au>Dueweke, Eric J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Atypical de Winter Presentation of Critical Left Anterior Descending Coronary Artery Occlusion</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><addtitle>Cureus</addtitle><date>2022-05-04</date><risdate>2022</risdate><volume>14</volume><issue>5</issue><spage>e24724</spage><pages>e24724-</pages><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>A 69-year-old male presented with substernal chest pain that started a few hours earlier. On arrival, the patient was hemodynamically stable, and the physical examination was unrevealing. Laboratory workup revealed an elevated high-sensitivity troponin, and an initial electrocardiogram (ECG) revealed tall, symmetric T-waves with preceding minor concave ST-segment elevations less than 1 mm in the precordial leads (V1-V6) and 0.5 mm ST elevation in the aVR. Due to concerning ECG changes, the patient was treated for a possible non-ST-segment elevation myocardial infarction. A loading dose of aspirin and clopidogrel was given and a heparin drip was initiated. However, the patient's chest pain persisted requiring multiple sublingual nitroglycerin tablets. Later, on further review of the ECGs, the presence of de Winter T-waves was noted and led to activation of the catheterization laboratory, and an urgent left heart catheterization (LHC) was done. LHC revealed a critical 90% occlusion of the left anterior descending artery, and a drug-eluting stent was placed. 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subjects | Acute coronary syndromes Angioplasty Anticoagulants Cardiac arrhythmia Cardiac catheterization Cardiology Cardiovascular disease Case reports Coronary vessels Electrocardiography Emergency medical care Emergency Medicine Heart attacks Heart rate Internal Medicine Intubation Laboratories Pain Patients |
title | Atypical de Winter Presentation of Critical Left Anterior Descending Coronary Artery Occlusion |
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