Application of molecular epidemiology to understanding campylobacteriosis in the Canterbury region of New Zealand

Pulsed-field gel electrophoresis genotypes of Campylobacter isolates from 603 human patients were compared with 485 isolates from retail offal (primarily chicken and lamb) to identify temporal clusters and possible sources of campylobacteriosis. Detailed epidemiological information was collected fro...

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Bibliographic Details
Published in:Epidemiology and infection 2013-06, Vol.141 (6), p.1253-1266
Main Authors: GILPIN, B. J., WALSHE, G., ON, S. L., SMITH, D., MARSHALL, J. C., FRENCH, N. P.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Animals
Biological and medical sciences
Campylobacter
Campylobacter - genetics
Campylobacter Infections - epidemiology
Campylobacter Infections - etiology
Campylobacter Infections - microbiology
Child
Child, Preschool
Disease
Electrophoresis, Gel, Pulsed-Field
Epidemics
Epidemiology
Female
Food Microbiology
Fundamental and applied biological sciences. Psychology
Gastrointestinal
Genotype
Humans
Infant
Infections
Laboratories
Male
Microbiology
Molecular Epidemiology - methods
New Zealand - epidemiology
Original Papers
Poultry
Prevalence
Risk factors
Sheep
Young Adult
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Summary:Pulsed-field gel electrophoresis genotypes of Campylobacter isolates from 603 human patients were compared with 485 isolates from retail offal (primarily chicken and lamb) to identify temporal clusters and possible sources of campylobacteriosis. Detailed epidemiological information was collected from 364 of the patients, and when combined with genotyping data allowed a putative transmission pathway of campylobacteriosis to be assigned for 88% of patients. The sources of infection were 47% food, 28% direct animal contact, 7% overseas travel, 4% person-to-person transmission and 3% water-related. A significant summer increase in campylobacteriosis cases was primarily attributed to an increase in food-related cases. Genotyping of isolates was essential for identifying the likely cause of infection for individuals. However, a more rapid and cheaper typing tool for Campylobacter is needed, which if applied to human and animal isolates on a routine basis could advance greatly our understanding of the ongoing problem of Campylobacter infection in New Zealand.
ISSN:0950-2688
1469-4409
DOI:10.1017/S0950268812001719