Signet ring cell gastric carcinoma with breast and leptomeningeal metastases: a case report

Gastric cancer is the 5 most common malignancy worldwide. Signet ring cell histology represents an aggressive subtype of gastric cancer, presenting at a younger age. Both breast and leptomeningeal metastases are rare locations of tumor dissemination, requiring correct and immediate diagnosis and tre...

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Bibliographic Details
Published in:Medicine and pharmacy reports 2022, Vol.95 (1), p.88-91
Main Authors: Moldovan, Tiberiu Rareş, Căinap, Călin, Fekete, Zsolt, Puşcaş, Emil, Roman, Andrei, Buiga, Rareş, Olteanu, Diana, Bota, Mădălina, Căinap, Simona, Bochiş, Ovidiu
Format: Article
Language:English
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Case Report
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Summary:Gastric cancer is the 5 most common malignancy worldwide. Signet ring cell histology represents an aggressive subtype of gastric cancer, presenting at a younger age. Both breast and leptomeningeal metastases are rare locations of tumor dissemination, requiring correct and immediate diagnosis and treatment. We present a case of a 45-year old female with signet ring cell gastric carcinoma who developed both left breast and leptomeningeal metastases, requiring multiple chemotherapy lines. As far as we know, this is the first published case in literature following multiple lines of treatment for both breast and leptomeningeal metastases from signet ring cell gastric carcinoma.
ISSN:2602-0807
2668-0572
DOI:10.15386/mpr-1654