Association between thrombocytopenia and the severity of Covid-19 infection among hospitalized Egyptian patients

• Published in: Annals of medicine and surgery 2022-07, Vol.79, p.103973-103973, Article 103973
• Main Authors: El-Khaiat, Mohsen M., El-lehlah, Ayman M., Kesheita, Manal A., Abdel-Samiee, Mohamed, Teima, Ahmed Abozaid Ahmed
• Format: Article
• Language: English
• Subjects: COVID-19; Cross-sectional Study; Disseminated intravascular coagulopathy; Severe acute respiratory syndrome; Thrombocytopenia
• ISSN: 2049-0801; 2049-0801
• DOI: 10.1016/j.amsu.2022.103973

COVID-19, which is caused by the corona virus 2 that causes severe acute respiratory syndrome, causes a respiratory and systemic illness that in 10–15% of patients escalates to a severe form of pneumonia. Thrombocytopenia is frequent in patients with COVID-19. We aimed to evaluate the association between thrombocytopenia and the severity of COVID-19 infection in hospitalized patients. A cross-sectional study was done on 800 Egyptian patients with confirmed covid-19 infection. They were divided into Group I (Mild): 200 symptomatic patients meeting the case definition for COVID-19 without radiological evidence of pneumonia or hypoxia. Group II (Moderate): 200 patients with clinical signs of non-severe pneumonia and radiological evidence of pneumonia. Group III (Severe): 200 patients with clinical signs of pneumonia plus: respiratory or lung dysfunction. Group IV: 200 critically ill patient in ICU: Acute respiratory distress syndrome (ARDS). Results: there was a highly statistically significant difference between the studied groups regarding thrombocytopenia (p