Risk factors of postoperative complications following total knee arthroplasty in Korea: A nationwide retrospective cohort study

The number of patients undergoing total knee arthroplasty (TKA) is gradually increasing and there is also increase in postoperative complications. The patient's demographic, socio-economic factors, hospital and clinical factors are all factors that can influence postoperative complications. The...

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Bibliographic Details
Published in:Medicine (Baltimore) 2021-12, Vol.100 (48), p.e28052-e28052
Main Authors: Ko, Min-Seok, Choi, Chong-Hyuk, Yoon, Han-Kook, Yoo, Ju-Hyung, Oh, Hyun-Cheol, Lee, Jin-Ho, Park, Sang-Hoon
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Arthroplasty, Replacement, Knee - adverse effects
Clinical Trial/Experimental Study
Cohort Studies
Female
Humans
Male
Middle Aged
Postoperative Complications - epidemiology
Prosthesis-Related Infections
Pulmonary Embolism
Retrospective Studies
Risk Factors
Sepsis
Stroke
Surgical Wound Infection - epidemiology
Surgical Wound Infection - etiology
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Summary:The number of patients undergoing total knee arthroplasty (TKA) is gradually increasing and there is also increase in postoperative complications. The patient's demographic, socio-economic factors, hospital and clinical factors are all factors that can influence postoperative complications. The purpose of this study was to determine the risk factors associated with complications following TKA in a large national cohort. Among patients diagnosed with primary knee arthrosis, a total of 560,954 patients older than 50 years who underwent TKA from January 1, 2005 to December 31, 2018 were included in the study. The risk of postoperative complications (surgical site infection, sepsis, cardiovascular complications, respiratory complications, pulmonary embolism, stroke, acute renal failure, periprosthetic joint infection, and periprosthetic fracture) were assessed with eight independent variables: gender, age, place of residence, household income, hospital bed size, procedure type (unilateral or bilateral, primary or revision TKA), length of stay (LOS), use of transfusion. Multivariable Cox Proportional Hazard model analysis was used. The significant predictors for complications (P 
ISSN:0025-7974
1536-5964
DOI:10.1097/MD.0000000000028052