Comparison of contrast-enhanced MRI features of the (teno)synovium in the wrist of patients with juvenile idiopathic arthritis and pediatric controls

To directly compare and describe the differences between juvenile idiopathic arthritis (JIA) patients and pediatric controls regarding features of the synovial and tenosynovial membrane on contrast-enhanced magnetic resonance imaging (MRI) of the wrist. T1-weighted contrast-enhanced MRI scans of 25...

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Bibliographic Details
Published in:Rheumatology international 2022-07, Vol.42 (7), p.1257-1264
Main Authors: van der Krogt, Jeffrey M. A., Verkuil, F., van Gulik, E. Charlotte, Hemke, Robert, van den Berg, J. Merlijn, Schonenberg-Meinema, Dieneke, Kindermann, Angelika, Dolman, Koert M., Benninga, Marc A., Kuijpers, Taco W., Maas, Mario, Nusman, Charlotte M.
Format: Article
Language:English
Subjects:
Arthritis
Imaging
Magnetic resonance imaging
Medicine
Medicine & Public Health
Pediatrics
Rheumatology
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Summary:To directly compare and describe the differences between juvenile idiopathic arthritis (JIA) patients and pediatric controls regarding features of the synovial and tenosynovial membrane on contrast-enhanced magnetic resonance imaging (MRI) of the wrist. T1-weighted contrast-enhanced MRI scans of 25 JIA patients with clinically active wrist arthritis and 25 children without a history of joint complaints nor any clinical signs of joint inflammation were evaluated by two readers blinded to clinical data. The synovium was scored at five anatomical sites based on thickening of the synovium (0–3 scale) and synovial enhancement (0–2 scale). Thickening and/or enhancement of the tenosynovium was scored at four anatomical sites using a 0–3 scale. Significantly higher scores for synovial thickening (median 4 vs. 1,  p  
ISSN:1437-160X
0172-8172
1437-160X
DOI:10.1007/s00296-021-05041-9