Neuropathic Pain Associated with COVID-19: a Systematic Review of Case Reports

Purpose of Review Researchers suggests that patients with COVID-19 develop neuropathic pain within weeks or months following infection and that patients with neuropathic pain and COVID-19 sometimes present with deterioration of neurologic complications and pain exacerbation. The objective of this sy...

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Bibliographic Details
Published in:Current pain and headache reports 2022-08, Vol.26 (8), p.595-603
Main Authors: Joshi, Deepika, Gyanpuri, Vyom, Pathak, Abhishek, Chaurasia, Rameshwar Nath, Mishra, Vijay Nath, Kumar, Anand, Singh, Varun Kumar, Dhiman, Neetu Rani
Format: Article
Language:English
Subjects:
Case reports
Coronaviruses
COVID-19
COVID-19 - complications
Humans
Internal Medicine
Medical research
Medicine
Medicine & Public Health
Neuralgia - etiology
Neuralgia, Postherpetic - complications
Neuropathic Pain (A Abd-Elsayed
Neuropathic Pain (A Abd-Elsayed, Section Editor)
Pain
Pain Medicine
Section Editor
Systematic review
Topical Collection on Neuropathic Pain
Trigeminal Neuralgia - complications
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Summary:Purpose of Review Researchers suggests that patients with COVID-19 develop neuropathic pain within weeks or months following infection and that patients with neuropathic pain and COVID-19 sometimes present with deterioration of neurologic complications and pain exacerbation. The objective of this systematic review is to discuss the case-reports having neuropathic pain during and after COVID-19 infection. Recent Findings Case reports that has described about patients getting neuropathy or neuropathic pain around the disease either immediately or late post COVID were included. The data was extracted and qualitatively synthesised. Literature was searched and 939 articles were found. 12 articles were screened as per the eligibility criteria and finally, 6 case reports on neuropathic pain in Covid-19 were selected from the database and manual search and finalised for analysis. 2 cases of herpes zoster and post herpetic neuralgia, 2 cases of intense burning pain, 1 case of trigeminal neuralgia and 1 of brachial plexopathy included for the review. Summary Covid 19 viral neurogenic invasion is something very newly discovered topic of discussion in the field of research. With the passage of time, more cases will emerge and more data will be available for research. The review is registered in Prospero with no. CRD42021257060.
ISSN:1531-3433
1534-3081
1534-3081
DOI:10.1007/s11916-022-01065-3