Untangling the Modern Treatment Paradigm for Unruptured Brain Arteriovenous Malformations

Brain arteriovenous malformations (AVMs) often present treatment challenges. Patients with unruptured AVMs must consider not only whether they want to be treated, but what treatment modality they would prefer. Vascular neurosurgeons, neurointerventional surgeons, and stereotactic radiosurgeons must...

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Bibliographic Details
Published in:Journal of personalized medicine 2022-05, Vol.12 (6), p.904
Main Authors: Morel, Brent C., Wittenberg, Blake, Hoffman, Jessa E., Case, David E., Folzenlogen, Zach, Roark, Christopher, Seinfeld, Joshua
Format: Article
Language:English
Subjects:
Aneurysms
Decision making
Embolization
Hemorrhage
Intervention
Microsurgery
Morbidity
Mortality
Patients
Precision medicine
Review
Stroke
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Summary:Brain arteriovenous malformations (AVMs) often present treatment challenges. Patients with unruptured AVMs must consider not only whether they want to be treated, but what treatment modality they would prefer. Vascular neurosurgeons, neurointerventional surgeons, and stereotactic radiosurgeons must in turn guide their patients through the most appropriate treatment course considering the risk of AVM rupture, an individual AVM’s characteristics, and patient preferences. In this review we will look at how the clinical trial “A Randomized Trial of Unruptured Brain Arteriovenous Malformations (ARUBA)” has influenced the approach to unruptured brain AVMs and the treatment modalities available to clinicians to deal with these formidable lesions.
ISSN:2075-4426
2075-4426
DOI:10.3390/jpm12060904