DOG1-Positive Primary Mesenteric Leiomyosarcoma: Report of a Case and Review of the Literature

The mesentery constitutes a common location for the metastatic spread of malignant gastrointestinal tumors. Primary mesenteric tumors, on the other hand, are very rare; lymphomas are the most common, followed by benign and malignant mesenchymal tumors. We present a case of a 43-year-old patient oper...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2022-05, Vol.14 (5)
Main Authors: Koufopoulos, Nektarios, Damaskou, Vasileia, Siozopoulou, Vasiliki, Kokoropoulos, Panagiotis, Gouloumis, Alina-Roxani, Arkadopoulos, Nikolaos, Panayiotides, Ioannis G
Format: Article
Language:English
Subjects:
Case reports
Colon
Fibroids
Gastrointestinal cancer
General Surgery
Literature reviews
Liver
Mesentery
Metastasis
Oncology
Pain
Pathology
Patients
Small intestine
Smooth muscle
Stains & staining
Tumors
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Description
Summary:The mesentery constitutes a common location for the metastatic spread of malignant gastrointestinal tumors. Primary mesenteric tumors, on the other hand, are very rare; lymphomas are the most common, followed by benign and malignant mesenchymal tumors. We present a case of a 43-year-old patient operated on for a primary mesenteric leiomyosarcoma with a positive immunostain for DOG1, despite having no KIT or PDGFRa mutations on molecular analysis. Moreover, we review the pertinent literature.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.25263