Chronic lymphocytic leukemia, a rare cause of spontaneous rupture of the spleen

• Published in: International journal of surgery case reports 2022-07, Vol.96, p.107315-107315, Article 107315
• Main Authors: Ayoub, Madani, Mabrouk, Mohamed Yassine, Abdelouahab, Hajar, Kamaoui, Imane, Achraf, Miry, Hamaz, Siham, Serraj, Khalid, Rachid, Jabi, Mohamed, Bouziane
• Format: Article
• Language: English
• Subjects: Case Report; Chronic lymphocytic leukemia; Prognosis; Spontaneous rupture of the spleen; Surgical treatment
• ISSN: 2210-2612; 2210-2612
• DOI: 10.1016/j.ijscr.2022.107315

Spleen Spontaneous Rupture SRS is a rare phenomenon in which the spleen ruptures without associated trauma. This pathology is rarely caused by Chronic Lymphocytic Leukemia. We present a case of a 59-year-old male patient with chronic Lymphocytic Leukemia, who was admitted with an acute abdomen whose clinical and paraclinical examinations revealed a spleen spontaneous rupture. The treatment consisted of a splenectomy. Spontaneous spleen rupture was first described by Rokitansky in 1861 and mentioned in many cases since, the common causes of non-traumatic Splenic rupture include myeloproliferative diseases, vasculitis, and infections. However, Chronic Lymphocytic Leukemia (CLL) remains an obscure cause of splenic rupture that requires unique attention. The diagnosis of splenic rupture should be considered in all patients with hematologic malignancies presenting with abrupt onset of abdominal pain, hemodynamic instability, or acute anemia. The choice between conservative treatment and splenectomy depends on different variables: the etiology of the SRS, the hemodynamic stability, the amount of packed red blood cells transfused. Thus, an interventional approach can be advocated for a spontaneous splenic rupture over nonoperative management. Splenic embolization can provide patients with the advantages of both operative splenectomy and conservative management. The mortality rate from SRS is 12.2 %. Neoplastic pathologies were most significantly associated with fatal outcomes. The high mortality rate seems to be mainly related to the delayed diagnosis and/or the severity of the underlying pathology. Given its seriousness, it requires a rapid diagnosis and adapted management. •Spontaneous rupture of the spleen is a rare phenomenon where the spleen ruptures without associated trauma.•chronic lymphocytic leukemia (CLL) remains an obscure cause of splenic rupture that requires unique attention•Clinical presentation is usually in the form of a severe abdominal syndrom with hemodynamic instability.•The choice of treatment: conservative, surgery or embolization depends on several factors.•The high mortality rate is related to delayed diagnosis and the severity of the underlying pathology.