Outcome of Treatment in Locally Advanced Upper Alveolar Carcinoma Extending to Infra-temporal Fossa

Squamous cell carcinoma of oral cavity has a high prevalence in our region. Upper alveolar cancers are uncommon but present with locally advanced disease extending to infra temporal fossa. The outcome of treatment in these tumors is poor. Surgery followed by adjuvant therapy is the mainstay of treat...

Full description

Saved in:
Bibliographic Details
Published in:Indian journal of otolaryngology, and head, and neck surgery and head, and neck surgery, 2022-06, Vol.74 (2), p.136-141
Main Authors: Brindha, H. S., Mohiyuddin, S. M. Azeem, Sagayaraj, A., Mohammadi, Kouser, Kalyani, R., Harshitha, N., Pillai, D. Aishwarya Raj, Suryanarayana, Ravishankar
Format: Article
Language:English
Subjects:
Cancer
Head and Neck Surgery
Lung cancer
Medicine
Medicine & Public Health
Metastasis
Oral cancer
Original
Original Article
Otorhinolaryngology
Radiation therapy
Squamous cell carcinoma
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Squamous cell carcinoma of oral cavity has a high prevalence in our region. Upper alveolar cancers are uncommon but present with locally advanced disease extending to infra temporal fossa. The outcome of treatment in these tumors is poor. Surgery followed by adjuvant therapy is the mainstay of treatment. We are presenting a retrospective analysis of outcome of treatment in 20 patients with locally advanced (T4b) upper alveolar carcinoma treated by infra-structure maxillectomy with compartment resection of infra-temporal fossa and neck dissection followed by adjuvant radiotherapy or radiotherapy with chemotherapy. Study period was from 2013 to 2018. Minimum follow up was 12 months and mean follow up 30 months. 12 patients are alive and disease free, 6 patients had local recurrence and 2 patients had regional recurrence with one having pulmonary metastasis. We observed that positive or close margins (
ISSN:2231-3796
0973-7707
DOI:10.1007/s12070-020-01810-3