Outcome of Treatment in Locally Advanced Upper Alveolar Carcinoma Extending to Infra-temporal Fossa

Squamous cell carcinoma of oral cavity has a high prevalence in our region. Upper alveolar cancers are uncommon but present with locally advanced disease extending to infra temporal fossa. The outcome of treatment in these tumors is poor. Surgery followed by adjuvant therapy is the mainstay of treat...

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Published in:Indian journal of otolaryngology, and head, and neck surgery and head, and neck surgery, 2022-06, Vol.74 (2), p.136-141
Main Authors: Brindha, H. S., Mohiyuddin, S. M. Azeem, Sagayaraj, A., Mohammadi, Kouser, Kalyani, R., Harshitha, N., Pillai, D. Aishwarya Raj, Suryanarayana, Ravishankar
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Language:English
Subjects:
Cancer
Head and Neck Surgery
Lung cancer
Medicine
Medicine & Public Health
Metastasis
Oral cancer
Original
Original Article
Otorhinolaryngology
Radiation therapy
Squamous cell carcinoma
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container_title Indian journal of otolaryngology, and head, and neck surgery
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creator Brindha, H. S.
Mohiyuddin, S. M. Azeem
Sagayaraj, A.
Mohammadi, Kouser
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Harshitha, N.
Pillai, D. Aishwarya Raj
Suryanarayana, Ravishankar
description Squamous cell carcinoma of oral cavity has a high prevalence in our region. Upper alveolar cancers are uncommon but present with locally advanced disease extending to infra temporal fossa. The outcome of treatment in these tumors is poor. Surgery followed by adjuvant therapy is the mainstay of treatment. We are presenting a retrospective analysis of outcome of treatment in 20 patients with locally advanced (T4b) upper alveolar carcinoma treated by infra-structure maxillectomy with compartment resection of infra-temporal fossa and neck dissection followed by adjuvant radiotherapy or radiotherapy with chemotherapy. Study period was from 2013 to 2018. Minimum follow up was 12 months and mean follow up 30 months. 12 patients are alive and disease free, 6 patients had local recurrence and 2 patients had regional recurrence with one having pulmonary metastasis. We observed that positive or close margins (
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subjects Cancer
Head and Neck Surgery
Lung cancer
Medicine
Medicine & Public Health
Metastasis
Oral cancer
Original
Original Article
Otorhinolaryngology
Radiation therapy
Squamous cell carcinoma
title Outcome of Treatment in Locally Advanced Upper Alveolar Carcinoma Extending to Infra-temporal Fossa
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