The Immediate Onset of Isolated and Unilateral Abducens Nerve Palsy Associated with COVID-19 Infection: A Case Report and Literature Review

Cranial nerve palsy associated with coronavirus disease 2019 (COVID-19) is rare. We herein report the first Asian case of the immediate onset of isolated and unilateral abducens nerve palsy (ANP) accompanied with COVID-19 infection. A 25-year-old man developed diplopia one day after the COVID-19 sym...

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Bibliographic Details
Published in:Internal Medicine 2022/06/01, Vol.61(11), pp.1761-1765
Main Authors: Kubota, Takafumi, Sugeno, Naoto, Sano, Hirohito, Murakami, Koji, Ikeda, Kensuke, Misu, Tatsuro, Aoki, Masashi
Format: Article
Language:English
Subjects:
Abducens Nerve
Abducens Nerve Diseases - etiology
abducens nerve palsy
Adult
anti-GQ1-b antibody
Ataxia
Case Report
Coronaviruses
COVID-19
COVID-19 - complications
Cranial nerves
Humans
Internal medicine
Literature reviews
Male
Miller Fisher syndrome
neurological complication
Paralysis
Patients
Quality of Life
SARS-CoV-2
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Summary:Cranial nerve palsy associated with coronavirus disease 2019 (COVID-19) is rare. We herein report the first Asian case of the immediate onset of isolated and unilateral abducens nerve palsy (ANP) accompanied with COVID-19 infection. A 25-year-old man developed diplopia one day after the COVID-19 symptom onset. Neurological examination revealed limitation of left eye abduction without ataxia and hyporeflexia. Negative anti-ganglioside antibody results and mild albuminocytological dissociation were noted. The patient was diagnosed with left ANP accompanied by COVID-19 infection. The ANP spontaneously recovered without treatment. ANP can develop during the early phase of COVID-19 infection and adversely affect patients' quality of life.
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.9308-22