Loading…

Adult Scurvy Presenting with Painful Purpura on the Legs

Prolonged vitamin C deficiency can result in numerous metabolic abnormalities like impaired tissue repair and defective collagen synthesis. This case report describes a middle-age Japanese man presenting painful purpura on his lower limbs, severe anemia, and altered consciousness. The patient had be...

Full description

Saved in:
Bibliographic Details
Published in:Internal Medicine 2022/06/15, Vol.61(12), pp.1913-1916
Main Authors: Tamura, Nayu, Obara, Takafumi, Yamada, Taihei, Nojima, Tsuyoshi, Nakamura, Shunsuke, Koide, Yasuhiro, Takaoka, Makoto, Naito, Hiromichi, Nakao, Atsunori
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c5691-e7c9af942558c68a94d397b60381606cc66bced7e17357b5d0646832db9c5f313
cites cdi_FETCH-LOGICAL-c5691-e7c9af942558c68a94d397b60381606cc66bced7e17357b5d0646832db9c5f313
container_end_page 1916
container_issue 12
container_start_page 1913
container_title Internal Medicine
container_volume 61
creator Tamura, Nayu
Obara, Takafumi
Yamada, Taihei
Nojima, Tsuyoshi
Nakamura, Shunsuke
Koide, Yasuhiro
Takaoka, Makoto
Naito, Hiromichi
Nakao, Atsunori
description Prolonged vitamin C deficiency can result in numerous metabolic abnormalities like impaired tissue repair and defective collagen synthesis. This case report describes a middle-age Japanese man presenting painful purpura on his lower limbs, severe anemia, and altered consciousness. The patient had been eating a selective diet lacking in vegetables and fruits since childhood. A serum analysis demonstrated a low level of vitamin C. The patient was treated with vitamin supplementation and psychological intervention. Scurvy is an under-considered illness with a favorable prognosis if diagnosed early while it is still sporadically encountered in some patients with malabsorption or malnutrition even in modern times.
doi_str_mv 10.2169/internalmedicine.8409-21
format article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9259809</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2683173373</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5691-e7c9af942558c68a94d397b60381606cc66bced7e17357b5d0646832db9c5f313</originalsourceid><addsrcrecordid>eNplkV2LEzEUhoMobq3-BQl4482s-Zh83QjL4hcUtqBeh0zmTJsyzdRkssv-e1Nai64QTi7Oc968Jy9CmJJrRqX5EOIMKbpxD33wIcK1bolpGH2GFpS3plGMi-doQQzVDavlCr3KeUcI18qwl-iKt0rJ1pAF0jd9GWf83Zd0_4jXCTLEOcQNfgjzFq9diEMZ8bqkQ0kOTxHPW8Ar2OTX6MXgxgxvzvcS_fz86cft12Z19-Xb7c2q8UIa2oDyxg2mZUJoL7Uzbc-N6mS1QiWR3kvZeegVUMWF6kRPZCs1Z31nvBg45Uv08aR7KF1d11d7yY32kMLepUc7uWD_7cSwtZvp3homjCamCrw_C6TpV4E8233IHsbRRZhKthVTmhEjVEXfPUF3Uzn-c6WqqWqR17NE-kT5NOWcYLiYocQe47FP47HHeGqrjr79e5nL4J88KnB3AnZ5dhu4AC7NwY_wv7KklrJjPT9xIf3WJQuR_wZA3K2J</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2683173373</pqid></control><display><type>article</type><title>Adult Scurvy Presenting with Painful Purpura on the Legs</title><source>PubMed Central (Open Access)</source><creator>Tamura, Nayu ; Obara, Takafumi ; Yamada, Taihei ; Nojima, Tsuyoshi ; Nakamura, Shunsuke ; Koide, Yasuhiro ; Takaoka, Makoto ; Naito, Hiromichi ; Nakao, Atsunori</creator><creatorcontrib>Tamura, Nayu ; Obara, Takafumi ; Yamada, Taihei ; Nojima, Tsuyoshi ; Nakamura, Shunsuke ; Koide, Yasuhiro ; Takaoka, Makoto ; Naito, Hiromichi ; Nakao, Atsunori</creatorcontrib><description>Prolonged vitamin C deficiency can result in numerous metabolic abnormalities like impaired tissue repair and defective collagen synthesis. This case report describes a middle-age Japanese man presenting painful purpura on his lower limbs, severe anemia, and altered consciousness. The patient had been eating a selective diet lacking in vegetables and fruits since childhood. A serum analysis demonstrated a low level of vitamin C. The patient was treated with vitamin supplementation and psychological intervention. Scurvy is an under-considered illness with a favorable prognosis if diagnosed early while it is still sporadically encountered in some patients with malabsorption or malnutrition even in modern times.</description><identifier>ISSN: 0918-2918</identifier><identifier>EISSN: 1349-7235</identifier><identifier>DOI: 10.2169/internalmedicine.8409-21</identifier><identifier>PMID: 34776490</identifier><language>eng</language><publisher>Japan: The Japanese Society of Internal Medicine</publisher><subject>anemia ; Ascorbic acid ; Case Report ; Children ; Collagen ; Dietary supplements ; Internal medicine ; Malabsorption ; Malnutrition ; Nutrient deficiency ; peliosis ; Purpura ; vitamin C</subject><ispartof>Internal Medicine, 2022/06/15, Vol.61(12), pp.1913-1916</ispartof><rights>2022 by The Japanese Society of Internal Medicine</rights><rights>Copyright Japan Science and Technology Agency 2022</rights><rights>Copyright © 2022 by The Japanese Society of Internal Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5691-e7c9af942558c68a94d397b60381606cc66bced7e17357b5d0646832db9c5f313</citedby><cites>FETCH-LOGICAL-c5691-e7c9af942558c68a94d397b60381606cc66bced7e17357b5d0646832db9c5f313</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259809/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259809/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,882,27906,27907,53773,53775</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34776490$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tamura, Nayu</creatorcontrib><creatorcontrib>Obara, Takafumi</creatorcontrib><creatorcontrib>Yamada, Taihei</creatorcontrib><creatorcontrib>Nojima, Tsuyoshi</creatorcontrib><creatorcontrib>Nakamura, Shunsuke</creatorcontrib><creatorcontrib>Koide, Yasuhiro</creatorcontrib><creatorcontrib>Takaoka, Makoto</creatorcontrib><creatorcontrib>Naito, Hiromichi</creatorcontrib><creatorcontrib>Nakao, Atsunori</creatorcontrib><title>Adult Scurvy Presenting with Painful Purpura on the Legs</title><title>Internal Medicine</title><addtitle>Intern. Med.</addtitle><description>Prolonged vitamin C deficiency can result in numerous metabolic abnormalities like impaired tissue repair and defective collagen synthesis. This case report describes a middle-age Japanese man presenting painful purpura on his lower limbs, severe anemia, and altered consciousness. The patient had been eating a selective diet lacking in vegetables and fruits since childhood. A serum analysis demonstrated a low level of vitamin C. The patient was treated with vitamin supplementation and psychological intervention. Scurvy is an under-considered illness with a favorable prognosis if diagnosed early while it is still sporadically encountered in some patients with malabsorption or malnutrition even in modern times.</description><subject>anemia</subject><subject>Ascorbic acid</subject><subject>Case Report</subject><subject>Children</subject><subject>Collagen</subject><subject>Dietary supplements</subject><subject>Internal medicine</subject><subject>Malabsorption</subject><subject>Malnutrition</subject><subject>Nutrient deficiency</subject><subject>peliosis</subject><subject>Purpura</subject><subject>vitamin C</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNplkV2LEzEUhoMobq3-BQl4482s-Zh83QjL4hcUtqBeh0zmTJsyzdRkssv-e1Nai64QTi7Oc968Jy9CmJJrRqX5EOIMKbpxD33wIcK1bolpGH2GFpS3plGMi-doQQzVDavlCr3KeUcI18qwl-iKt0rJ1pAF0jd9GWf83Zd0_4jXCTLEOcQNfgjzFq9diEMZ8bqkQ0kOTxHPW8Ar2OTX6MXgxgxvzvcS_fz86cft12Z19-Xb7c2q8UIa2oDyxg2mZUJoL7Uzbc-N6mS1QiWR3kvZeegVUMWF6kRPZCs1Z31nvBg45Uv08aR7KF1d11d7yY32kMLepUc7uWD_7cSwtZvp3homjCamCrw_C6TpV4E8233IHsbRRZhKthVTmhEjVEXfPUF3Uzn-c6WqqWqR17NE-kT5NOWcYLiYocQe47FP47HHeGqrjr79e5nL4J88KnB3AnZ5dhu4AC7NwY_wv7KklrJjPT9xIf3WJQuR_wZA3K2J</recordid><startdate>20220615</startdate><enddate>20220615</enddate><creator>Tamura, Nayu</creator><creator>Obara, Takafumi</creator><creator>Yamada, Taihei</creator><creator>Nojima, Tsuyoshi</creator><creator>Nakamura, Shunsuke</creator><creator>Koide, Yasuhiro</creator><creator>Takaoka, Makoto</creator><creator>Naito, Hiromichi</creator><creator>Nakao, Atsunori</creator><general>The Japanese Society of Internal Medicine</general><general>Japan Science and Technology Agency</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20220615</creationdate><title>Adult Scurvy Presenting with Painful Purpura on the Legs</title><author>Tamura, Nayu ; Obara, Takafumi ; Yamada, Taihei ; Nojima, Tsuyoshi ; Nakamura, Shunsuke ; Koide, Yasuhiro ; Takaoka, Makoto ; Naito, Hiromichi ; Nakao, Atsunori</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5691-e7c9af942558c68a94d397b60381606cc66bced7e17357b5d0646832db9c5f313</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>anemia</topic><topic>Ascorbic acid</topic><topic>Case Report</topic><topic>Children</topic><topic>Collagen</topic><topic>Dietary supplements</topic><topic>Internal medicine</topic><topic>Malabsorption</topic><topic>Malnutrition</topic><topic>Nutrient deficiency</topic><topic>peliosis</topic><topic>Purpura</topic><topic>vitamin C</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tamura, Nayu</creatorcontrib><creatorcontrib>Obara, Takafumi</creatorcontrib><creatorcontrib>Yamada, Taihei</creatorcontrib><creatorcontrib>Nojima, Tsuyoshi</creatorcontrib><creatorcontrib>Nakamura, Shunsuke</creatorcontrib><creatorcontrib>Koide, Yasuhiro</creatorcontrib><creatorcontrib>Takaoka, Makoto</creatorcontrib><creatorcontrib>Naito, Hiromichi</creatorcontrib><creatorcontrib>Nakao, Atsunori</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Internal Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tamura, Nayu</au><au>Obara, Takafumi</au><au>Yamada, Taihei</au><au>Nojima, Tsuyoshi</au><au>Nakamura, Shunsuke</au><au>Koide, Yasuhiro</au><au>Takaoka, Makoto</au><au>Naito, Hiromichi</au><au>Nakao, Atsunori</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Adult Scurvy Presenting with Painful Purpura on the Legs</atitle><jtitle>Internal Medicine</jtitle><addtitle>Intern. Med.</addtitle><date>2022-06-15</date><risdate>2022</risdate><volume>61</volume><issue>12</issue><spage>1913</spage><epage>1916</epage><pages>1913-1916</pages><artnum>8409-21</artnum><issn>0918-2918</issn><eissn>1349-7235</eissn><abstract>Prolonged vitamin C deficiency can result in numerous metabolic abnormalities like impaired tissue repair and defective collagen synthesis. This case report describes a middle-age Japanese man presenting painful purpura on his lower limbs, severe anemia, and altered consciousness. The patient had been eating a selective diet lacking in vegetables and fruits since childhood. A serum analysis demonstrated a low level of vitamin C. The patient was treated with vitamin supplementation and psychological intervention. Scurvy is an under-considered illness with a favorable prognosis if diagnosed early while it is still sporadically encountered in some patients with malabsorption or malnutrition even in modern times.</abstract><cop>Japan</cop><pub>The Japanese Society of Internal Medicine</pub><pmid>34776490</pmid><doi>10.2169/internalmedicine.8409-21</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0918-2918
ispartof Internal Medicine, 2022/06/15, Vol.61(12), pp.1913-1916
issn 0918-2918
1349-7235
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9259809
source PubMed Central (Open Access)
subjects anemia
Ascorbic acid
Case Report
Children
Collagen
Dietary supplements
Internal medicine
Malabsorption
Malnutrition
Nutrient deficiency
peliosis
Purpura
vitamin C
title Adult Scurvy Presenting with Painful Purpura on the Legs
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-17T09%3A18%3A22IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Adult%20Scurvy%20Presenting%20with%20Painful%20Purpura%20on%20the%20Legs&rft.jtitle=Internal%20Medicine&rft.au=Tamura,%20Nayu&rft.date=2022-06-15&rft.volume=61&rft.issue=12&rft.spage=1913&rft.epage=1916&rft.pages=1913-1916&rft.artnum=8409-21&rft.issn=0918-2918&rft.eissn=1349-7235&rft_id=info:doi/10.2169/internalmedicine.8409-21&rft_dat=%3Cproquest_pubme%3E2683173373%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c5691-e7c9af942558c68a94d397b60381606cc66bced7e17357b5d0646832db9c5f313%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2683173373&rft_id=info:pmid/34776490&rfr_iscdi=true