The 2021 World Health Organization Classification of Tumors of the Central Nervous System: What Neuroradiologists Need to Know

Neuroradiologists play a key role in brain tumor diagnosis and management. Staying current with the latest classification systems and diagnostic markers is important to provide optimal patient care. Publication of the 2016 World Health Organization Classification of Tumors of the Central Nervous Sys...

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Bibliographic Details
Published in:American journal of neuroradiology : AJNR 2022-07, Vol.43 (7), p.928-937
Main Authors: Osborn, A G, Louis, D N, Poussaint, T Y, Linscott, L L, Salzman, K L
Format: Article
Language:English
Subjects:
Adult Brain
Brain - pathology
Brain Neoplasms - pathology
Central Nervous System
Central Nervous System Neoplasms - diagnostic imaging
Humans
World Health Organization
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Summary:Neuroradiologists play a key role in brain tumor diagnosis and management. Staying current with the latest classification systems and diagnostic markers is important to provide optimal patient care. Publication of the 2016 World Health Organization Classification of Tumors of the Central Nervous System introduced a paradigm shift in the diagnosis of CNS neoplasms. For the first time, both histologic features and genetic alterations were incorporated into the diagnostic framework, classifying and grading brain tumors. The newly published 2021 World Health Organization Classification of Tumors of the Central Nervous System, May 2021, 5th edition, has added even more molecular features and updated pathologic diagnoses. We present, summarize, and illustrate the most salient aspects of the new 5th edition. We have selected the key "must know" topics for practicing neuroradiologists.
ISSN:0195-6108
1936-959X
DOI:10.3174/ajnr.a7462