Serum protein electrophoresis in 26 dogs with chronic hepatitis

Serum protein electrophoresis (SPE) shows the distribution of protein fractions, helping clinicians to characterize some pathologic processes. Information is lacking in the literature about SPE alterations in dogs with chronic hepatitis (CH). Our aim was to describe SPE alterations in canine CH, to...

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Bibliographic Details
Published in:Journal of veterinary diagnostic investigation 2022-07, Vol.34 (4), p.738-741
Main Authors: Gori, Eleonora, Pierini, Alessio, Tulone, Fiorenza, Abramo, Francesca, Marchetti, Veronica
Format: Article
Language:English
Subjects:
Animals
Blood Proteins - analysis
Brief Reports
Dog Diseases - diagnosis
Dogs
Electrophoresis - veterinary
gamma-Globulins
Globulins
Hepatitis, Chronic - diagnosis
Hepatitis, Chronic - veterinary
Retrospective Studies
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Summary:Serum protein electrophoresis (SPE) shows the distribution of protein fractions, helping clinicians to characterize some pathologic processes. Information is lacking in the literature about SPE alterations in dogs with chronic hepatitis (CH). Our aim was to describe SPE alterations in canine CH, to compare SPE results to histologic scores, and to study SPE trends during follow-up. We reviewed retrospectively case data from dogs with a histologic diagnosis of CH. Only cases with SPE, CBC, and serum chemistry results available were included. Dogs were divided into subgroups based on histologic necroinflammatory activity (A) and fibrosis (F) scores (groups A0-1 and A>1; groups F
ISSN:1040-6387
1943-4936
DOI:10.1177/10406387221101547