‘When Cryptococcus strikes and lupus is found’: a unique covert unveiling of systemic lupus erythematosus presenting as subacute meningitis

Cryptococcal neoformans is a rare fungal pathogen that has been associated with immunocompromised individuals. Due to its rare occurrence, clinicians have a low index of suspicion for diagnosis, which can lead to increased morbidity and mortality. We present an 81-year-old fully functional woman wit...

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Bibliographic Details
Published in:Therapeutic advances in chronic disease 2022-07, Vol.13
Main Authors: Essien, Francis, Westbrook, Marquise, Wolfley, Graey, Patterson, Shane, Carrol, Matthew
Format: Article
Language:English
Subjects:
Case Report
Fungal infections
Lupus
Medical diagnosis
Meningitis
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Summary:Cryptococcal neoformans is a rare fungal pathogen that has been associated with immunocompromised individuals. Due to its rare occurrence, clinicians have a low index of suspicion for diagnosis, which can lead to increased morbidity and mortality. We present an 81-year-old fully functional woman with no known predisposing risk factors or previous immunocompromising conditions who was found to have cryptococcal meningitis on cerebrospinal fluid analysis in the setting of newly diagnosed uncontrolled type 2 diabetes and systemic lupus erythematosus (SLE).
ISSN:2040-6223
2040-6231
DOI:10.1177/20406223221102784