Intracranial lymphoma in human immunodeficiency virus-infected patients: A diagnostic dilemma?

Primary central nervous system (CNS) lymphoma is an aggressive malignancy which constitutes one of the acquired immunodeficiency syndrome -defining illnesses. Early diagnosis and timely management can increase the chances of cure. Although many times the diagnosis is straightforward, we present a ca...

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Published in:Indian journal of sexually transmitted diseases and AIDS 2022-01, Vol.43 (1), p.82-84
Main Authors: Harjani, Rajkumar, Hinduja, Ritika, Iyer, Asha
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Antiretroviral drugs
Case Reports
Medical diagnosis
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Hinduja, Ritika
Iyer, Asha
description Primary central nervous system (CNS) lymphoma is an aggressive malignancy which constitutes one of the acquired immunodeficiency syndrome -defining illnesses. Early diagnosis and timely management can increase the chances of cure. Although many times the diagnosis is straightforward, we present a case of primary CNS lymphoma in a human immunodeficiency virus--positive individual which posed as a major diagnostic dilemma with initially normal imaging findings. A 42-year-old male presented with unremitting fever and a perianal ulcer for 3 months. A battery of diagnostic tests were negative, including a positron emission tomography-computed tomography scan and a magnetic resonance imaging brain. With unresolving symptoms and a high index of suspicion as he developed dizziness and loss of balance, the same were repeated which confirmed a space-occupying lesion in the cerebellum. Although treatment was instituted, the patient did not recover and died in the 4th month of treatment.
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subjects Antiretroviral drugs
Case Reports
Medical diagnosis
title Intracranial lymphoma in human immunodeficiency virus-infected patients: A diagnostic dilemma?
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