Post-traumatic stress in adults with 22q11.2 deletion syndrome

22q11.2 deletion syndrome (22q11.2DS) is associated with an elevated genetic risk of several psychiatric disorders. However, the prevalence of post-traumatic stress disorder (PTSD) in individuals with 22q11.2DS has been reported to be only 0.9%; this is lower than that of the general population (3.9...

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Bibliographic Details
Published in:BJPsych open 2022-07, Vol.8 (4), p.e126-e126, Article e126
Main Authors: von Scheibler, Emma N. M. M., van Amelsvoort, Thérèse A. M. J., Vingerhoets, Claudia, van Eeghen, Agnies M., Boot, Erik
Format: Article
Language:English
Subjects:
Adults
Behavior modification
Clinics
Eye movements
Intellectual disabilities
Intellectual Disability
Medical ethics
Mental disorders
Patients
Population
Post traumatic stress disorder
Psychotherapy
Short Report
Trauma
Violence
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Summary:22q11.2 deletion syndrome (22q11.2DS) is associated with an elevated genetic risk of several psychiatric disorders. However, the prevalence of post-traumatic stress disorder (PTSD) in individuals with 22q11.2DS has been reported to be only 0.9%; this is lower than that of the general population (3.9%). We explored the occurrence of PTSD and traumatic events in a Dutch cohort of 112 adults with 22q11.2DS, and found PTSD in 8.0%, traumatic events in 20.5% and trauma-focused treatment in 17.9% of patients. Our novel findings suggest that PTSD may be underdiagnosed in individuals with 22q11.2DS. Clinicians and other caregivers should be alert to trauma in this population in order to enable treatment and minimise psychiatric burden.
ISSN:2056-4724
2056-4724
DOI:10.1192/bjo.2022.525