A carvacrol‐based product reduces Campylobacter jejuni load and alters microbiota composition in the caeca of chickens

Aim This study was conducted to test the ability of a carvacrol‐based formulation (Phodé, France) to decrease the C. jejuni caecal load in inoculated broiler chickens and to study the impact of the C. jejuni inoculation alone or combined with the product, on the caecal microbiota. Methods and Result...

Full description

Saved in:
Bibliographic Details
Published in:Journal of applied microbiology 2022-06, Vol.132 (6), p.4501-4516
Main Authors: Allaoua, Marion, Bonnafé, Elsa, Etienne, Pierre, Noirot, Virginie, Gabarrou, Jean‐François, Castinel, Adrien, Pascal, Géraldine, Darbot, Vincent, Treilhou, Michel, Combes, Sylvie
Format: Article
Language:English
Subjects:
16Sr RNA gene sequencing
Animal biology
Antiinfectives and antibacterials
Bacteriology
Biotechnology
broiler chicken
Campylobacter
Campylobacter jejuni
Carvacrol
Chickens
essential oil
feed additive
Food and Nutrition
foodborne disease
Functional analysis
Gene sequencing
Inoculation
Life Sciences
Microbiology and Parasitology
microbiome
Microbiota
Microorganisms
Mode of action
Original
PICRUSt2
Pollution control
Poultry
rRNA 16S
Veterinary medicine and animal Health
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Aim This study was conducted to test the ability of a carvacrol‐based formulation (Phodé, France) to decrease the C. jejuni caecal load in inoculated broiler chickens and to study the impact of the C. jejuni inoculation alone or combined with the product, on the caecal microbiota. Methods and Results On day 1, chickens were either fed a control feed or the same diet supplemented with a carvacrol‐based product. On day 21, the carvacrol‐supplemented chickens and half of the non‐supplemented chickens were inoculated with C. jejuni (108 CFU). Quantitative PCR was used to quantify C. jejuni in chicken caecal samples and 16S rRNA gene sequencing was carried out at 25, 31 and 35 days of age. A significant decrease of 1.4 log of the C. jejuni caecal load was observed in 35‐day‐old chickens supplemented with the product, compared to the inoculated and unsupplemented group (p 
ISSN:1364-5072
1365-2672
DOI:10.1111/jam.15521