Factors Associated with Variability in Pulse Wave Transit Time Using Pulse Oximetry: A Retrospective Study

Pulse wave transit time (PWTT) is the time difference between the occurrence of an R-wave on an electrocardiogram and the detection of pulsatile signals on a pulse oximeter, which reflects changes in blood pressure (BP) corresponding to the vessel wall compliance. However, the factors affecting PWTT...

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Bibliographic Details
Published in:Journal of clinical medicine 2022-07, Vol.11 (14), p.3963
Main Authors: Budiman, Hilmanda, Wakita, Ryo, Ito, Takaya, Maeda, Shigeru
Format: Article
Language:English
Subjects:
Anesthesia
Anesthesiology
Blood pressure
Body mass index
Catheters
Clinical medicine
Electrocardiography
Heart rate
Local anesthesia
Medical personnel
Medical records
Patients
Systemic diseases
Vital signs
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Summary:Pulse wave transit time (PWTT) is the time difference between the occurrence of an R-wave on an electrocardiogram and the detection of pulsatile signals on a pulse oximeter, which reflects changes in blood pressure (BP) corresponding to the vessel wall compliance. However, the factors affecting PWTT variability have not been determined. Thus, we investigated the BP changes associated with variations in PWTT and identified the clinical characteristics associated with these variations. Data related to 605 cases of dental procedures performed under intravenous conscious sedation from April 2020 to November 2021 were collected, and 485 cases were enrolled. Heart rate, systolic blood pressure before and after local anesthesia (LA) administration, and crest and trough PWTT waves during LA administration were recorded. Thereafter, PWTT variability was calculated; cases were divided into two groups: large PWTT variability (LPV, n = 357) and small PWTT variability (SPV, n = 128). The index of large PWTT variability could not detect changes in BP. Logistic regression analysis revealed that factors, such as LA use, age, hypertension, and dental treatment phobia were associated with PWTT variability. The use of epinephrine more than 36.25 µg in each LA resulted in PWTT variability of more than 15 ms.
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm11143963