Tissue Adhesives in Reconstructive and Aesthetic Surgery—Application of Silk Fibroin-Based Biomaterials

Tissue adhesives have been successfully used in various kind of surgeries such as oral and maxillofacial surgery for some time. They serve as a substitute for suturing of tissues and shorten treatment time. Besides synthetic-based adhesives, a number of biological-based formulations are finding thei...

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Bibliographic Details
Published in:International journal of molecular sciences 2022-07, Vol.23 (14), p.7687
Main Authors: Smeets, Ralf, Tauer, Nathalie, Vollkommer, Tobias, Gosau, Martin, Henningsen, Anders, Hartjen, Philip, Früh, Leonie, Beikler, Thomas, Stürmer, Ewa K., Rutkowski, Rico, Grust, Audrey Laure Céline, Fuest, Sandra, Gaudin, Robert, Aavani, Farzaneh
Format: Article
Language:English
Subjects:
Adhesives
Biomaterials
Biomedical materials
Bond strength
Maxillofacial
Mechanical properties
Needlestick injuries
Plastic surgery
Proteins
Reconstructive surgery
Review
Sealing compounds
Silk fibroin
Streptococcus infections
Surgery
Sutures
Tensile strength
Wound healing
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Summary:Tissue adhesives have been successfully used in various kind of surgeries such as oral and maxillofacial surgery for some time. They serve as a substitute for suturing of tissues and shorten treatment time. Besides synthetic-based adhesives, a number of biological-based formulations are finding their way into research and clinical application. In natural adhesives, proteins play a crucial role, mediating adhesion and cohesion at the same time. Silk fibroin, as a natural biomaterial, represents an interesting alternative to conventional medical adhesives. Here, the most commonly used bioadhesives as well as the potential of silk fibroin as natural adhesives will be discussed.
ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms23147687