Predictors for Returning to Paid Work after Transient Ischemic Attack and Minor Ischemic Stroke

This study aims to determine which factors within the first week after a first-ever transient ischemic attack (TIA) or minor ischemic stroke (MIS) are associated with stroke survivors’ ability to return to either partial or full time paid external work (RTpW). In this single-center prospective cohor...

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Bibliographic Details
Published in:Journal of personalized medicine 2022-07, Vol.12 (7), p.1109
Main Authors: Wicht, Corentin A, Chavan, Camille F, Annoni, Jean-Marie, Balmer, Philippe, Aellen, Jérôme, Humm, Andrea M, Crettaz von Roten, Fabienne, Spierer, Lucas, Medlin, Friedrich
Format: Article
Language:English
Subjects:
Cholesterol
Cognitive ability
Demographics
Hypercholesterolemia
Hyperlipidemia
Hypertension
Ischemia
Low density lipoprotein
Multivariate analysis
Outpatient care facilities
Patients
Population
Precision medicine
Questionnaires
Statins
Stroke
Transient ischemic attack
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Summary:This study aims to determine which factors within the first week after a first-ever transient ischemic attack (TIA) or minor ischemic stroke (MIS) are associated with stroke survivors’ ability to return to either partial or full time paid external work (RTpW). In this single-center prospective cohort study, we recruited 88 patients with first-ever TIA or MIS (NIHSS ≤ 5). Bivariate analyses were conducted between patients that did (RTpW) or did not return to paid work (noRTpW) within 7 days after stroke onset and at 3-months follow-up. Then, we conducted multivariate logistic and negative binomial regression analyses assessing (i) which factors are associated with RTpW at 3 months (ii) the likelihood that patients would RTpW at 3 months and (iii) the number of months necessary to RTpW. Overall, 43.2% of the patients did not RTpW at 3 months. At 3-months follow-up, higher anxiety/depression and fatigue-related disabilities were associated with noRTpW. Multivariate analysis showed that higher NIHSS scores at onset and hyperlipidemia (LDL cholesterol > 2.6 mmol/L or statins at stroke onset) were associated with noRTpW at 3 months. Stroke severity and/or newly diagnosed hypercholesterolemia at stroke onset in TIA or MIS patients were associated with not returning to paid work at 3 months.
ISSN:2075-4426
2075-4426
DOI:10.3390/jpm12071109