Consequences of cervical pessary for subsequent pregnancy: follow‐up of randomized clinical trial (ProTWIN)

ABSTRACT Objective To evaluate the effect of cervical pessary, as a strategy to prevent preterm birth (PTB), on the outcome of subsequent pregnancy and maternal quality of life 4 years after the index twin pregnancy. Methods Between 2009 and 2012, the ProTWIN trial randomized women with a multiple p...

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Bibliographic Details
Published in:Ultrasound in obstetrics & gynecology 2022-06, Vol.59 (6), p.771-777
Main Authors: Limburg Stirum, E. V. J., Zegveld, S. J., Simons, N. E., Boer, M. A., Pajkrt, E., Mol, B. W. J., Oudijk, M. A., Hooft, J.
Format: Article
Language:English
Subjects:
Cervix
follow‐up
Gynecology
Obstetrics
Original Paper
Original Papers
Participation
pessary
Pregnancy
Premature birth
preterm birth
Quality assessment
Quality of life
Subgroups
twin pregnancy
Ultrasonic imaging
Ultrasound
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Summary:ABSTRACT Objective To evaluate the effect of cervical pessary, as a strategy to prevent preterm birth (PTB), on the outcome of subsequent pregnancy and maternal quality of life 4 years after the index twin pregnancy. Methods Between 2009 and 2012, the ProTWIN trial randomized women with a multiple pregnancy to pessary use vs standard care for the prevention of PTB. The trial showed no benefit in unselected women with a twin pregnancy, but showed a 60% reduction in poor perinatal outcomes in favor of the pessary group in the subgroup of women with a mid‐trimester short cervix (cervical length
ISSN:0960-7692
1469-0705
DOI:10.1002/uog.24821