Percutaneous Left Atrial Appendage Closure in a Patient with Diffuse Alveolar Hemorrhaging Associated with Anticoagulant Therapy and Atrial Fibrillation

Diffuse alveolar hemorrhaging (DAH) due to oral anticoagulation (OAC) is a life-threatening condition that leads to severe respiratory failure. There is a clinical dilemma in that OAC-induced DAH often forces the discontinuation of OAC therapy and the administration of high-dose corticosteroids, whi...

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Published in:Internal Medicine 2022/07/01, Vol.61(13), pp.2045-2050
Main Authors: Ogoshi, Takaaki, Fukunaga, Masato, Suzuki, Yu, Taura, Yusuke, Yatera, Kazuhiro
Format: Article
Language:English
Subjects:
Alveoli
Anticoagulants
atrial fibrillation
Cardiovascular diseases
Case Report
corticosteroid
Corticosteroids
diffuse alveolar hemorrhaging
Fibrillation
Internal medicine
Occlusion
Patients
percutaneous left atrial appendage closure
respiratory failure
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cited_by cdi_FETCH-LOGICAL-c587t-ec8c2be7b533cff7190b7f2e3ac09a0ea76c3e5b4d248f6b1562ddf4383c99a93
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description Diffuse alveolar hemorrhaging (DAH) due to oral anticoagulation (OAC) is a life-threatening condition that leads to severe respiratory failure. There is a clinical dilemma in that OAC-induced DAH often forces the discontinuation of OAC therapy and the administration of high-dose corticosteroids, which increases the risk of stroke and cardiovascular events. We herein report the first case of OAC-induced DAH and atrial fibrillation (AF) in a patient who completely discontinued OAC therapy and high-dose corticosteroids after experiencing percutaneous left atrial appendage (LAA) occlusion. This case suggests that percutaneous LAA closure may aid in the management of OAC-induced DAH and AF.
doi_str_mv 10.2169/internalmedicine.8551-21
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subjects Alveoli
Anticoagulants
atrial fibrillation
Cardiovascular diseases
Case Report
corticosteroid
Corticosteroids
diffuse alveolar hemorrhaging
Fibrillation
Internal medicine
Occlusion
Patients
percutaneous left atrial appendage closure
respiratory failure
title Percutaneous Left Atrial Appendage Closure in a Patient with Diffuse Alveolar Hemorrhaging Associated with Anticoagulant Therapy and Atrial Fibrillation
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