Morbidity and mortality in adults with congenital heart defects in the third and fourth life decade

Objectives The population of adults with congenital heart defects (ACHD) is continuously growing. Data on morbidity and mortality of ACHD are limited. This longitudinal observational study examined a group of ACHD with surgically corrected or palliated congenital heart defects (CHD) during a 15-year...

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Published in:Clinical research in cardiology 2022-08, Vol.111 (8), p.900-911
Main Authors: Müller, Matthias J., Norozi, Kambiz, Caroline, Jonas, Sedlak, Nicole, Bock, Jonas, Paul, Thomas, Geyer, Siegfried, Dellas, Claudia
Format: Article
Language:English
Subjects:
Ablation
Adults
Cardiology
Defects
Electrophysiological recording
Heart
Heart surgery
Medical instruments
Medicine
Medicine & Public Health
Morbidity
Mortality
Observational studies
Original Paper
Palliation
Patients
Surgery
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Summary:Objectives The population of adults with congenital heart defects (ACHD) is continuously growing. Data on morbidity and mortality of ACHD are limited. This longitudinal observational study examined a group of ACHD with surgically corrected or palliated congenital heart defects (CHD) during a 15-year period. Methods ACHD that had participated in the initial study were invited for a follow-up examination. Mortality and hospitalization data were compared with a healthy control group. Results From 05/2017 to 04/2019 a total of 249/364 (68%) ACHD participated in the follow-up study: 21% had mild, 60% moderate and 19% severe CHD. During the observational period, 290 health incidents occurred (cardiac catheterization 37%, cardiovascular surgery 27%, electrophysiological study/ablation 20%, catheter interventional treatment 14%, non-cardiac surgery 3%). Events were more frequent in ACHD with moderate (53%) and severe (87%) compared to those with mild CHD ( p  
ISSN:1861-0684
1861-0692
DOI:10.1007/s00392-022-01989-1