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Back Cover: Amplification‐Free Detection of SARS‐CoV‐2 and Respiratory Syncytial Virus Using CRISPR Cas13a and Graphene Field‐Effect Transistors (Angew. Chem. Int. Ed. 32/2022)

Nucleic acid detection plays a critical role in medical diagnostics, environmental monitoring, and food safety. In their Research Article (e202203826), Xue Gao, Yi Zhang and co‐workers developed a new biosensor for amplification‐free nucleic acid detection via harnessing the trans‐cleavage mechanism...

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Bibliographic Details
Published in:Angewandte Chemie International Edition 2022-08, Vol.61 (32), p.n/a
Main Authors: Li, Huijie, Yang, Jie, Wu, Guangfu, Weng, Zhengyan, Song, Yang, Zhang, Yuxuan, Vanegas, Jeffrey A., Avery, Lori, Gao, Zan, Sun, He, Chen, Yupeng, Dieckhaus, Kevin D., Gao, Xue, Zhang, Yi
Format: Article
Language:English
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Summary:Nucleic acid detection plays a critical role in medical diagnostics, environmental monitoring, and food safety. In their Research Article (e202203826), Xue Gao, Yi Zhang and co‐workers developed a new biosensor for amplification‐free nucleic acid detection via harnessing the trans‐cleavage mechanism of Cas13a and ultrasensitive graphene field‐effect transistors (gFETs). The illustration shows the Cas13a‐mediated RNA trans‐cleavage on a gFET surface for sensor signal transduction.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.202209501