Incidence and Clinical Characteristics of Severe Acute Respiratory Syndrome Coronavirus 2 Infection After Vaccination in Children

The objective of this single-center cohort study was to characterize the frequency, clinical characteristics, and molecular epidemiology of pediatric severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection after vaccination. Between May 15, 2021, and January 1, 2022, 171 children expe...

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Bibliographic Details
Published in:The Journal of pediatrics 2022-12, Vol.251, p.196-201.e4
Main Authors: Reyna, Megan E., Edward, Priya R., Ozer, Egon A., Simons, Lacy M., Hultquist, Judd F., Lorenzo-Redondo, Ramon, Patel, Ami B., Kociolek, Larry K.
Format: Article
Language:English
Subjects:
breakthrough
Brief Reports
Child
Cohort Studies
COVID-19
COVID-19 - epidemiology
COVID-19 - prevention & control
COVID-19 Vaccines
Humans
Incidence
pediatric
SARS-CoV-2
Vaccination
vaccine
Vaccine Efficacy
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Summary:The objective of this single-center cohort study was to characterize the frequency, clinical characteristics, and molecular epidemiology of pediatric severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection after vaccination. Between May 15, 2021, and January 1, 2022, 171 children experienced SARS-CoV-2 infection postvaccination, 146 (86%) following the Omicron variant predominance. Outcomes were generally mild and comparable before and after Omicron predominance.
ISSN:0022-3476
1097-6833
1097-6833
DOI:10.1016/j.jpeds.2022.07.056