Effects of Green Tea and Green Tea Incorporated in Nanoparticle Lyotropic Liquid Crystal on Exercise Adaptations: A High-Intensity Interval Training Pre-Clinical Study

Green tea (GT) is a natural antioxidant, sensitive to oxidation after preparation. Lyotropic liquid crystals (LLCs) are nanostructured systems used to incorporate bioactive compounds. High-intensity interval training (HIIT) is a workout modality that increases the production of reactive oxygen speci...

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Published in:Nutrients 2022-08, Vol.14 (15), p.3226
Main Authors: Nieri, Vitor, de Souza, Juliana Ferreira, Segato, Talita Cristina Mena, Caetano, Érika Leão Ajala, Leite, Fernanda Gomes, Chaud, Marco Vinícius, Grotto, Denise
Format: Article
Language:English
Subjects:
Adaptation
Animals
Anticoagulants
Antioxidants
Bioactive compounds
Bioavailability
Blood
Body mass
Body weight
Body weight gain
Crystals
Drug delivery systems
Exercise
Green tea
Hematology
Hypertrophy
Interval training
Kinases
Liquid crystals
Muscles
Nanoparticles
Oxidation
Physiology
Poloxamers
Polyphenols
Reactive oxygen species
Surfactants
Tea
Triglycerides
Weight reduction
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container_start_page 3226
container_title Nutrients
container_volume 14
creator Nieri, Vitor
de Souza, Juliana Ferreira
Segato, Talita Cristina Mena
Caetano, Érika Leão Ajala
Leite, Fernanda Gomes
Chaud, Marco Vinícius
Grotto, Denise
description Green tea (GT) is a natural antioxidant, sensitive to oxidation after preparation. Lyotropic liquid crystals (LLCs) are nanostructured systems used to incorporate bioactive compounds. High-intensity interval training (HIIT) is a workout modality that increases the production of reactive oxygen species (ROS). Thus, this research aimed to compare the effects of GT and GT loaded in LLC in animals subjected to HIIT, considering hematological, biochemical and histological parameters, redox status, and body mass. Monoolein, GT in infusion and Poloxamer 407 were mixed to obtain nanoparticles of LLC (NP-LLC). Healthy male rats were randomized into six groups (n = 6/group): Control (C), GT, GT-NP-LLC, Exercise (Ex), GT+Ex, GT-NP-LLC+Ex. Body weight was significantly lower in all groups subjected to HIIT compared to C. The percentages of body mass reduction were 11.3, 13.0, 10.0 and 11.0% for Ex, GT+Ex, GT-NP-LLC and GT-NP-LLC+Ex, respectively, compared to control. GT-NP-LLC and Ex reduced triglycerides compared to C. GT and GT-NP-LLC supplementation combined with HIIT presented higher muscle hypertrophy (25 and 21%, respectively), better physical conditioning, and reduced body weight gain rate compared to HIIT by itself. Moreover, the effects of GT-NP-LLC itself on body mass and biochemical parameters are promising, suggesting NP-LLC could improve the bioavailability of GT.
doi_str_mv 10.3390/nu14153226
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Lyotropic liquid crystals (LLCs) are nanostructured systems used to incorporate bioactive compounds. High-intensity interval training (HIIT) is a workout modality that increases the production of reactive oxygen species (ROS). Thus, this research aimed to compare the effects of GT and GT loaded in LLC in animals subjected to HIIT, considering hematological, biochemical and histological parameters, redox status, and body mass. Monoolein, GT in infusion and Poloxamer 407 were mixed to obtain nanoparticles of LLC (NP-LLC). Healthy male rats were randomized into six groups (n = 6/group): Control (C), GT, GT-NP-LLC, Exercise (Ex), GT+Ex, GT-NP-LLC+Ex. Body weight was significantly lower in all groups subjected to HIIT compared to C. The percentages of body mass reduction were 11.3, 13.0, 10.0 and 11.0% for Ex, GT+Ex, GT-NP-LLC and GT-NP-LLC+Ex, respectively, compared to control. GT-NP-LLC and Ex reduced triglycerides compared to C. GT and GT-NP-LLC supplementation combined with HIIT presented higher muscle hypertrophy (25 and 21%, respectively), better physical conditioning, and reduced body weight gain rate compared to HIIT by itself. 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subjects Adaptation
Animals
Anticoagulants
Antioxidants
Bioactive compounds
Bioavailability
Blood
Body mass
Body weight
Body weight gain
Crystals
Drug delivery systems
Exercise
Green tea
Hematology
Hypertrophy
Interval training
Kinases
Liquid crystals
Muscles
Nanoparticles
Oxidation
Physiology
Poloxamers
Polyphenols
Reactive oxygen species
Surfactants
Tea
Triglycerides
Weight reduction
title Effects of Green Tea and Green Tea Incorporated in Nanoparticle Lyotropic Liquid Crystal on Exercise Adaptations: A High-Intensity Interval Training Pre-Clinical Study
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