The Delayed Nephrogram: Point-of-care Quantitative Measurement, Validation as an Indicator of Obstruction, and Novel Use as a Predictor of Renal Functional Impairment

Delayed and diminished nephrograms can be quantified easily at the point of care. An inter-renal difference of 15 Hounsfield units is highly specific for obstruction. Delayed nephrograms are more specific indicators of renal functional impairment than the degree of pelvic dilation. The diagnostic va...

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Published in:European urology focus 2022-11, Vol.8 (6), p.1809-1815
Main Authors: Strother, Marshall C., Cho, Eric Y., Loecher, Matt, Strauss, David, Chandra, Akhil, Handorf, Elizabeth, Yu, Jian, Chen, David Y.T., Uzzo, Robert, Levin, Laura, Anaokar, Jordan, Kutikov, Alexander
Format: Article
Language:English
Subjects:
Computed tomography
Diuretic renography
Humans
Hydronephrosis
Mercaptoacetyltriglycine
Point-of-Care Systems
Reproducibility of Results
Ureteral obstruction
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Summary:Delayed and diminished nephrograms can be quantified easily at the point of care. An inter-renal difference of 15 Hounsfield units is highly specific for obstruction. Delayed nephrograms are more specific indicators of renal functional impairment than the degree of pelvic dilation. The diagnostic value of delayed nephrograms on contrast-enhanced computed tomography has not been studied rigorously. To develop a method for quantitatively assessing delayed and diminished nephrograms (DDNs) easily at the point of care and to assess the association of DDNs with renal obstruction and renal function. Data were reviewed from 76 patients who underwent a contrast-enhanced computed tomography scan within 30 days of a technetium-99m mercaptoacetyltriglycine diuretic renal scintigraphy (MAG3-DRS) which showed at least one kidney to have normal drainage (T1/2
ISSN:2405-4569
2405-4569
DOI:10.1016/j.euf.2022.01.019