Changes of Serum D-Dimer, NT-proBNP, and Troponin I Levels in Patients with Acute Aortic Dissection and the Clinical Significance

Objective. To investigate the changes in blood D-dimer (D-D), high-sensitivity troponin I (hs-cTnI), and N-terminal B-type brain natriuretic peptide (NT-proBNP) levels in patients with acute aortic dissection (AAD) and its clinical significance. Methods. Forty patients with AAD diagnosed in our hosp...

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Published in:Evidence-based complementary and alternative medicine 2022-08, Vol.2022, p.8309505-5
Main Authors: Xu, Zexiang, Wei, Meiyu, Guo, Xin, Zhang, Qing, Ma, Yankun, Gao, Zhisheng, Teng, Zhen
Format: Article
Language:English
Subjects:
Abdomen
Angina pectoris
Anticoagulants
Aorta
Aortic dissection
Asymmetry
Back pain
Biotechnology
Blood pressure
Brain natriuretic peptide
Calcium-binding protein
Chi-square test
Clinical significance
Coronary vessels
Death
Diabetes
Diagnosis
Disease
Dissection
Females
Gender
Heart attacks
Hypertension
Males
Medical imaging
Medical prognosis
Mortality
Patients
Prognosis
Pulmonary embolisms
Statistical analysis
Survival
Troponin
Troponin I
Veins & arteries
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Summary:Objective. To investigate the changes in blood D-dimer (D-D), high-sensitivity troponin I (hs-cTnI), and N-terminal B-type brain natriuretic peptide (NT-proBNP) levels in patients with acute aortic dissection (AAD) and its clinical significance. Methods. Forty patients with AAD diagnosed in our hospital from January 2018 to December 2019 were selected as the observation group, and 40 patients with chest pain and non-AAD treated in our hospital during the same period were included in the control group. The patients were subdivided into a death group and a survival group as per the prognosis. The clinical symptoms and signs of the two groups of patients upon admission were observed, and the levels of D-D, hs-cTnI, and NT-proBNP were determined. The differences in clinical data, plasma D-D, hs-cTnI, and NT-proBNP levels between the two groups of patients were analyzed. Results. The clinical data and physical signs were homogeneous between the two groups (P>0.05), while a significant elevation in the level of hs-cTnI in the control group was observed 24 h after admission (P
ISSN:1741-427X
1741-4288
DOI:10.1155/2022/8309505