Delayed Vasovagal Reaction with Reflex Syncope Following COVID-19 Vaccination

Coronavirus disease 2019 (COVID-19) has become a pandemic, and vaccines remain the only effective tools available for ending it. However, their side effects, such as syncope, which mimics sudden cardiac death, are serious concerns. We herein report 6 cases of delayed vasovagal syncope and presyncope...

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Bibliographic Details
Published in:Internal Medicine 2022/07/15, Vol.61(14), pp.2167-2170
Main Authors: Takase, Bonpei, Hayashi, Katsumi, Takei, Satoko, Hisada, Tetsuya, Masaki, Nobuyuki, Nagata, Masayoshi
Format: Article
Language:English
Subjects:
anxiety autonomic reflex
Case Report
Coronaviruses
COVID-19
Influenza
Internal medicine
Patients
SARS-CoV-2 vaccine
side effect
Vaccines
vasovagal response
Vasovagal syncope
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Summary:Coronavirus disease 2019 (COVID-19) has become a pandemic, and vaccines remain the only effective tools available for ending it. However, their side effects, such as syncope, which mimics sudden cardiac death, are serious concerns. We herein report 6 cases of delayed vasovagal syncope and presyncope (VVR) caused by COVID-19 vaccination among 25,530 COVID-19 patients. The prevalence of delayed VVR due to COVID-19 vaccination was 0.026%. In addition, no delayed VVR was found among 17,386 patients who received the influenza vaccine. Delayed VVR is likely to be overlooked if medical staff are not aware of this symptom. This report provides significant information regarding effects of COVID-19 vaccination.
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.9318-21