Serum protein concentration and amino acid profile of HIV/HBV co-infected subjects on HAART in Plateau State, Nigeria

Background: Human immunodeficiency virus (HIV) and hepatitis B virus (HBV) are currently two important blood-borne human pathogens of major public health concern with high prevalence rates in Africa. Objectives: The study assessed the impact of HIV and HBV mono- and co-infections on serum total prot...

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Bibliographic Details
Published in:African health sciences 2022-03, Vol.22 (1), p.418-30
Main Authors: Uzoma Igwe, Chidi, Emagba Ewuga, Emmanuel, Onyedikachi Ujowundu, Cosmas, Oparaji Onyeocha, Ignatius, Adaku Onwuliri, Viola
Format: Article
Language:English
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Summary:Background: Human immunodeficiency virus (HIV) and hepatitis B virus (HBV) are currently two important blood-borne human pathogens of major public health concern with high prevalence rates in Africa. Objectives: The study assessed the impact of HIV and HBV mono- and co-infections on serum total protein, albumin, globulin fractions and plasma free amino acids concentrations. Methods: This was a cross-sectional study on adult (25 – 64 years old) patients on Highly Active Antiretroviral Therapy attending AIDS Preventive Initiative in Nigeria Centre, Jos University Teaching Hospital, Plateau State, Nigeria. It involved 80 subjects; 20 HIV/HBV co-infected, 20 each of HIV and HBV mono-infected controls, and 20 seronegative controls. Results: Significant (p
ISSN:1680-6905
1680-6905
1729-0503
DOI:10.4314/ahs.v22i1.51