Modal analysis of novel coronavirus (SARS COV-2) using finite element methodology

Many new engineering and scientific innovations have been proposed to date to passivate the novel coronavirus (SARS CoV-2), with the aim of curing the related disease that is now recognised as COVID-19. Currently, vaccine development remains the most reliable solution available. Efforts to provide s...

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Bibliographic Details
Published in:Journal of the mechanical behavior of biomedical materials 2022-11, Vol.135, p.105406-105406, Article 105406
Main Authors: Warsame, Caaisha, Valerini, Daniele, Llavori, Iñigo, Barber, Asa H., Goel, Saurav
Format: Article
Language:English
Subjects:
COVID-19
Finite Element Analysis
Finite element analysis (FEA)
Humans
Modal analysis
Natural frequencies
Pandemics - prevention & control
SARS-CoV-2
Spike Glycoprotein, Coronavirus - metabolism
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Summary:Many new engineering and scientific innovations have been proposed to date to passivate the novel coronavirus (SARS CoV-2), with the aim of curing the related disease that is now recognised as COVID-19. Currently, vaccine development remains the most reliable solution available. Efforts to provide solutions as alternatives to vaccinations are growing and include established control of behaviours such as self-isolation, social distancing, employing facial masks and use of antimicrobial surfaces. The work here proposes a novel engineering method employing the concept of resonant frequencies to denature SARS CoV-2. Specifically, “modal analysis” is used to computationally analyse the Eigenvalues and Eigenvectors i.e. frequencies and mode shapes to denature COVID-19. An average virion dimension of 63 nm with spike proteins number 6, 7 and 8 were examined, which revealed a natural frequency of a single virus in the range of 88–125 MHz. The information derived about the natural frequency of the virus through this study will open newer ways to exploit medical solutions to combat future pandemics. [Display omitted] •Modal Analysis on SARS-CoV-2 model was performed to investigate the natural frequencies and mode shapes.•The frequency range to denature SARS CoV-2 was found to be in the range of 88.52–125.13 MHz.•This testbed provides a ground for doing field trials.•This method could also represent an effective and safe route to sustainably sterilize surfaces.
ISSN:1751-6161
1878-0180
DOI:10.1016/j.jmbbm.2022.105406