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Primary signet-ring cell carcinoma of the cecum: A rare case report

Primary SRCC is a rare histological colorectal cancer subtype. It is characterized by distinct clinical presentation. This case report describes a rare case of a Primary Signet-ring cell carcinoma of the cecum. A 37-year-old man came to the emergency department with bowel obstruction and altered gen...

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Bibliographic Details
Published in:International journal of surgery case reports 2022-09, Vol.98, p.107466, Article 107466
Main Authors: Anas, Derkaoui, Tarik, Deflaoui, Yassine, Mabrouk Mohamed, Haitam, Soussan, Ayoub, Madani, Magouri, Oumaima, Rachid, Jabi, Mohammed, Bouziane
Format: Article
Language:English
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Summary:Primary SRCC is a rare histological colorectal cancer subtype. It is characterized by distinct clinical presentation. This case report describes a rare case of a Primary Signet-ring cell carcinoma of the cecum. A 37-year-old man came to the emergency department with bowel obstruction and altered general condition. The abdominal CT scan showed an intestinal occlusion upstream a thickening of the cecum. An exploratory laparotomy found a distention of the bowl with a suspect thickening of the cecum. The patient underwent a right ileo-colectomy and ileocolostomy. Histologic analysis of the operatory specimen confirmed the diagnosis of a primary Signet-ring cell carcinoma of the cecum. The recovery was uneventful, and the patient is in good health after six –months of follow-up. After completing the chemotherapy, the patient is scheduled for a colonoscopy and reversal of colostomy. Colorectal primary signet ring cell carcinoma (SRCC) is a rare entity, and it is associated with poor prognosis compared with common colorectal adenocarcinomas. characterized by distinct clinical presentation, with very poor response rates. Primary SRCC is an aggressive histological type of colon cancer and it is associated with a poor prognosis. There are no conclusive guidelines for the treatment of this type of tumor. •Signet ring cell carcinoma (SRCC) is an extremely rare histological type for colon cancer.•SRCC is characterized by distinct clinical presentation, and it is associated with poor prognosis.•Characterized by distinct clinical presentation.•There are no conclusive guidelines for the treatment of this type of tumor.
ISSN:2210-2612
2210-2612
DOI:10.1016/j.ijscr.2022.107466