Advances in Transversal Topics Applicable to the Care of Bladder Cancer Patients in the Real-World Setting

Recommendations regarding transversal topics applicable to bladder cancer patients independent of tumor grade and stage were established by members of the Spanish Oncology Genitourinary Multidisciplinary Working Group (SOGUG). Liquid biopsy in urine and blood samples is useful in the surveillance of...

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Bibliographic Details
Published in:Cancers 2022-08, Vol.14 (16), p.3968
Main Authors: Garrido Siles, Marga, López-Beltran, Antonio, Pelechano, Paula, García Vicente, Ana María, Gironés Sarrió, Regina, González-Haba Peña, Eva, Rodríguez Antolín, Alfredo, Zapatero, Almudena, Arranz, José Ángel, Climent, Miguel Ángel
Format: Article
Language:English
Subjects:
Accuracy
Biomarkers
Biopsy
Bladder cancer
Cancer
Cancer therapies
Care and treatment
Diagnosis
Forecasts and trends
Immune checkpoint
Magnetic resonance imaging
Medical prognosis
Mutation
Oncology
Patients
Positron emission tomography
Precision medicine
Review
Surveillance
Tomography
Tumors
Ultrasonic imaging
Urine
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Summary:Recommendations regarding transversal topics applicable to bladder cancer patients independent of tumor grade and stage were established by members of the Spanish Oncology Genitourinary Multidisciplinary Working Group (SOGUG). Liquid biopsy in urine and blood samples is useful in the surveillance of non-muscle-invasive and muscle-invasive bladder cancer, respectively. Multiparametric MRI is an accurate, faster and non-invasive staging method overcoming the understaging risk of other procedures. The combination of FDG-PET/MRI could improve diagnostic reliability, but definite criteria for imaging interpretation are still unclear. Hospital oncology pharmacists as members of tumor committees improve the safety of drug use. Additionally, safety recommendations during BCG preparation should be strictly followed. The initial evaluation of patients with bladder cancer should include a multidimensional geriatric assessment. Orthotopic neobladder reconstruction should be offered to motivated patients with full information of self-care requirements. Bladder-sparing protocols, including chemoradiation therapy and immune checkpoints inhibitors (ICIs), should be implemented in centers with well-coordinated multidisciplinary teams and offered to selected patients. The optimal strategy of treatment with ICIs should be defined from the initial diagnostic phase with indications based on scientific evidence. Centralized protocols combined with the experience of professional groups are needed for the integral care of bladder cancer patients.
ISSN:2072-6694
2072-6694
DOI:10.3390/cancers14163968