The New Precision Stewards?

The precision health era is likely to reduce and respond to antimicrobial resistance (AMR). Our stewardship and precision efforts share terminology, seeking to deliver the “right drug, at the right dose, at the right time.” Already, rapid diagnostic testing, phylogenetic surveillance, and real-time...

Full description

Saved in:
Bibliographic Details
Published in:Journal of personalized medicine 2022-08, Vol.12 (8), p.1308
Main Authors: Meagher, Karen M., Watson, Sara, Suh, Gina A., Virk, Abinash
Format: Article
Language:English
Subjects:
Academic disciplines
Ambulatory care
Antimicrobial agents
Antimicrobial resistance
Attitudes
Coronaviruses
COVID-19
Drug dosages
Drug resistance
Ethics
Gap analysis
Genetic engineering
Genetic Information Nondiscrimination Act 2008-US
Genetic research
Genomes
Genomics
Health disparities
Hospitals
Infectious diseases
Literacy
Nosocomial infections
Pathogens
Patient safety
Phylogeny
Precision medicine
Public health
Science
Social sciences
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The precision health era is likely to reduce and respond to antimicrobial resistance (AMR). Our stewardship and precision efforts share terminology, seeking to deliver the “right drug, at the right dose, at the right time.” Already, rapid diagnostic testing, phylogenetic surveillance, and real-time outbreak response provide just a few examples of molecular advances we dub “precision stewardship.” However, the AMR causal factors range from the molecular to that of global health policy. Mirroring the cross-sectoral nature of AMR science, the research addressing the ethical, legal and social implications (ELSI) of AMR ranges across academic scholarship. As the rise of AMR is accompanied by an escalating sense of its moral and social significance, what is needed is a parallel field of study. In this paper, we offer a gap analysis of this terrain, or an agenda for “the ELSI of precision stewardship.” In the first section, we discuss the accomplishments of a multi-decade U.S. national investment in ELSI research attending to the advances in human genetics. In the next section, we provide an overview of distinct ELSI topics pertinent to AMR. The distinctiveness of an ELSI agenda for precision stewardship suggests new opportunities for collaboration to build the stewardship teams of the future.
ISSN:2075-4426
2075-4426
DOI:10.3390/jpm12081308