COVID-19 postacute care major organ damage: a systematic review

BACKGROUNDMajor organ complications have been reported in patients hospitalised for COVID-19; most studies lacked controls. OBJECTIVEExamine major organ damage postdischarge among adults hospitalised for COVID-19 versus non-COVID-19 controls. DATA SOURCESMEDLINE, Embase and Cochrane Library from 1 J...

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Published in:BMJ open 2022-08, Vol.12 (8), p.e061245-e061245
Main Authors: Greer, Nancy, Bart, Bradley, Billington, Charles J, Diem, Susan J, Ensrud, Kristine E, Kaka, Anjum, Klein, Mark, Melzer, Anne C, Reule, Scott, Shaukat, Aasma, Sheets, Kerry, Starks, Jamie, Vardeny, Orly, McKenzie, Lauren, Stroebel, Benjamin, Macdonald, Roderick, Sowerby, Katie, Duan-Porter, Wei, Wilt, Timothy J
Format: Article
Language:English
Subjects:
Infectious Diseases
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Summary:BACKGROUNDMajor organ complications have been reported in patients hospitalised for COVID-19; most studies lacked controls. OBJECTIVEExamine major organ damage postdischarge among adults hospitalised for COVID-19 versus non-COVID-19 controls. DATA SOURCESMEDLINE, Embase and Cochrane Library from 1 January 2020 to 19 May 2021. STUDY ELIGIBILITY CRITERIAEnglish language studies of adults discharged from hospital for COVID-19; reporting major organ damage. Single review of abstracts; independent dual review of full text. STUDY APPRAISAL AND SYNTHESIS METHODSStudy quality was assessed using the Joanna Briggs Institute Appraisal Checklist for Cohort Studies. Outcome data were not pooled due to heterogeneity in populations, study designs and outcome assessment methods; findings are narratively synthesised. RESULTSOf 124 studies in a full evidence report, 9 included non-COVID controls and are described here. Four of the nine (three USA, one UK) used large administrative databases. Four of the remaining five studies enrolled
ISSN:2044-6055
2044-6055
DOI:10.1136/bmjopen-2022-061245