Hypertension Management in Patients with Chronic Kidney Disease

Hypertension and chronic kidney disease are closely linked. Patients with chronic kidney disease have hypertension almost universally and uncontrolled hypertension accelerates the decline in kidney function. The pathophysiology of hypertension in chronic kidney disease is complex, but is largely rel...

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Bibliographic Details
Published in:Methodist DeBakey cardiovascular journal 2022-09, Vol.18 (4), p.41-49
Main Authors: Hebert, Sean A., Ibrahim, Hassan N.
Format: Article
Language:English
Subjects:
Review
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Summary:Hypertension and chronic kidney disease are closely linked. Patients with chronic kidney disease have hypertension almost universally and uncontrolled hypertension accelerates the decline in kidney function. The pathophysiology of hypertension in chronic kidney disease is complex, but is largely related to reduced nephron mass, sympathetic nervous system overactivation, involvement of the renin-angiotensin-aldosterone system, and generalized endothelial dysfunction. Consensus guidelines for blood pressure targets have adopted a blood pressure
ISSN:1947-6108
1947-6094
1947-6108
DOI:10.14797/mdcvj.1119