Aorta to proper hepatic artery bypass with total pancreatectomy and celiac axis resection (TP-CAR) in a patient with locally advanced pancreas adenocarcinoma

• Published in: International journal of surgery case reports 2022-09, Vol.98, p.107544, Article 107544
• Main Authors: Tsiotos, Gregory G., Ballian, Nikiforos, Milas, Fotios, Peraki, Evangelia, Kostopanagiotou, Georgia, Tsigaridas, Konstantinos
• Format: Article
• Language: English
• Subjects: Case Report; Celiac artery resection; DP-CAR; Hepatic artery resection; Proper hepatic artery
• ISSN: 2210-2612; 2210-2612
• DOI: 10.1016/j.ijscr.2022.107544

Total pancreatectomy with en-bloc celiac axis resection (TP-CAR) and interposition graft placement between the aorta and the proper hepatic artery is a technically demanding, very uncommonly performed operation, even in high-volume pancreatic centers. We present, in clinical and technical detail, a patient with locally advanced adenocarcinoma of the pancreatic body and neck involving the celiac and common hepatic arteries and portal vein, who underwent neoadjuvant chemotherapy and radiation with very good response, followed by TP-CAR and aorto-proper hepatic artery bypass using saphenous vein graft. The patient had an uneventful intraoperative and postoperative course, short hospital stay, and histology consistent with a curative resection. TP-CAR with common hepatic artery resection and proper hepatic artery reconstruction in patients with locally advanced pancreatic body cancer after appropriate neoadjuvant therapy can be performed safely and be potentially curative in centers with an established track record in advanced pancreatic surgery involving major peripancreatic vessels. TP-CAR with proper hepatic artery reconstruction is a rare but potentially curative operation for selected patients with otherwise unresectable pancreatic adenocarcinoma. •TP-CAR and aorto-PHA bypass graft: A very rare, technically demanding operation with significant morbidity & mortality•This operation may provide curative (R0) resection of an otherwise unresectable cancer•Our patient had optimal perioperative outcome and excellent histology result•To the best of our knowledge this is the first TP-CAR with aorto-PHA bypass graft case in Greece