126 Antioxidant-Containing Kibble Supplemented to Adult Cats Elicited Improvements in Antioxidant Outcomes and C-Reactive Protein

• Published in: Journal of animal science 2022-09, Vol.100 (Supplement_3), p.58-58
• Main Authors: Panasevich, Matthew, Daristotle, Leighann, Lin, Ching-Yen, Frantz, Nolan
• Format: Article
• Language: English
• Subjects: Oral Presentations
• ISSN: 0021-8812; 1525-3163
• DOI: 10.1093/jas/skac247.113

The objective of this study was to evaluate oxidative health biomarkers in healthy male and female adult cats (n=30; 10 male and 20 female, avg age and BW + SD 3.34 ± 3.19 years; 3.85 ± 1.07 kg) fed an adult maintenance diet (Blue Buffalo Healthy Living Adult Chicken and Brown Rice) without (control diet) and supplemented with an antioxidant-containing kibble (test diet; proprietary blend containing blueberries, cranberries, and other antioxidant-containing ingredients). Both diets analyzed as 35.9% crude protein, 19.8% fat, 2.1% crude fiber, 6.4% moisture, 28.6% carbohydrate as-is. We hypothesized that test feeding would reduce serum pro-oxidative biomarkers, compared with control feeding. The study protocol was first approved by the Institutional Animal Care and Use Committee. All cats were fed a base kennel maintenance diet (no added antioxidants beyond maintenance requirements) for 14d before treatment phase. Animals were then randomized to control or test for a 28d treatment period in a randomized cross-over design. Base kennel maintenance diet was provided for a 14d washout, followed by another treatment period. Serum was collected on days 0, 14, and 28 of for biomarkers analysis. Data were analyzed as a mixed models 2-way ANCOVA (SAS v9.4). Significant differences between treatments were set at P