The spike hypothesis in vaccine-induced adverse effects: questions and answers

Trougakos and colleagues recently discussed the role of coronavirus disease 2019 (COVID-19) mRNA vaccine-induced spike (S) protein in adverse effects following vaccination [1]. We would like hereafter to answer one of their outstanding questions requiring response to improve efficacy and safety of C...

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Bibliographic Details
Published in:Trends in molecular medicine 2022-10, Vol.28 (10), p.797-799
Main Authors: Cosentino, Marco, Marino, Franca
Format: Article
Language:English
Subjects:
COVID-19 - prevention & control
COVID-19 Vaccines - adverse effects
Humans
Letter
mRNA Vaccines
Vaccination - adverse effects
Vaccines, Synthetic
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Summary:Trougakos and colleagues recently discussed the role of coronavirus disease 2019 (COVID-19) mRNA vaccine-induced spike (S) protein in adverse effects following vaccination [1]. We would like hereafter to answer one of their outstanding questions requiring response to improve efficacy and safety of COVID-19 vaccines, and to propose an additional question along with its possible answer.
ISSN:1471-4914
1471-499X
1471-499X
DOI:10.1016/j.molmed.2022.07.009