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Estimated GFR, Albuminuria, and Physical Function: The Brain in Kidney Disease (BRINK) Cohort Study
Chronic kidney disease (CKD) is associated with impaired physical performance. However, the association between albuminuria, a marker of vascular endothelial dysfunction, and physical performance has not been fully characterized. We hypothesized that estimated glomerular filtration rate (eGFR) and a...
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Published in: | Kidney medicine 2022-10, Vol.4 (10), p.100531-100531, Article 100531 |
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Main Authors: | , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | Chronic kidney disease (CKD) is associated with impaired physical performance. However, the association between albuminuria, a marker of vascular endothelial dysfunction, and physical performance has not been fully characterized. We hypothesized that estimated glomerular filtration rate (eGFR) and albuminuria would be independently associated with physical performance.
Cross-sectional analysis.
A total of 571 adults with and without CKD.
Creatinine-based eGFR (eGFRCr) and cystatin C-based eGFR (eGFRCysC) and urine albumin to creatinine ratio (UACR).
Short Physical Performance Battery (SPPB).
Univariate and multivariable logistic regression models were used to examine associations of eGFR and UACR with impaired physical performance.
Of the 571 participants (mean age, 69.3 years), 157 (27.5%) had eGFRCr (mL/min/1.73m2)Â |
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ISSN: | 2590-0595 2590-0595 |
DOI: | 10.1016/j.xkme.2022.100531 |