Bacteriocins as Potential Therapeutic Approaches in the Treatment of Various Cancers: A Review of In Vitro Studies

Cancer is regarded as one of the most common and leading causes of death. Despite the availability of conventional treatments against cancer cells, current treatments are not the optimal treatment for cancer as they possess the possibility of causing various unwanted side effects to the body. As a r...

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Bibliographic Details
Published in:Cancers 2022-09, Vol.14 (19), p.4758
Main Authors: Molujin, Arnold Marshall, Abbasiliasi, Sahar, Nurdin, Armania, Lee, Ping-Chin, Gansau, Jualang Azlan, Jawan, Roslina
Format: Article
Language:English
Subjects:
Antimicrobial peptides
Bacteriocins
Cancer
Cancer therapies
Care and treatment
Cell division
Cell growth
Chemotherapy
Colorectal cancer
Cytotoxicity
Drug dosages
Enzymes
Health aspects
Metastasis
Mutation
Patients
Peptides
Radiation therapy
Review
Side effects
Surgery
Tomography
Tumor cell lines
Tumors
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Summary:Cancer is regarded as one of the most common and leading causes of death. Despite the availability of conventional treatments against cancer cells, current treatments are not the optimal treatment for cancer as they possess the possibility of causing various unwanted side effects to the body. As a result, this prompts a search for an alternative treatment without exhibiting any additional side effects. One of the promising novel therapeutic candidates against cancer is an antimicrobial peptide produced by bacteria called bacteriocin. It is a non-toxic peptide that is reported to exhibit potency against cancer cell lines. Experimental studies have outlined the therapeutic potential of bacteriocin against various cancer cell lines. In this review article, the paper focuses on the various bacteriocins and their cytotoxic effects, mode of action and efficacies as therapeutic agents against various cancer cell lines.
ISSN:2072-6694
2072-6694
DOI:10.3390/cancers14194758