Medication Non-Adherence in Rheumatology, Oncology and Cardiology: A Review of the Literature of Risk Factors and Potential Interventions

Medication adherence is directly associated with health outcomes. Adherence has been reviewed extensively; however, most studies provide a narrow scope of the problem, covering a specific disease or treatment. This project's objective was to identify risk factors for non-adherence in the fields...

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Bibliographic Details
Published in:International journal of environmental research and public health 2022-09, Vol.19 (19), p.12036
Main Authors: Gil-Guillen, Vicente F, Balsa, Alejandro, Bernárdez, Beatriz, Valdés Y Llorca, Carmen, Márquez-Contreras, Emilio, de la Haba-Rodríguez, Juan, Castellano, Jose M, Gómez-Martínez, Jesús
Format: Article
Language:English
Subjects:
Cardiology
Chronic illnesses
Drug stores
Hospitals
Humans
Literature reviews
Medical treatment
Medication Adherence
Oncology
Patient compliance
Review
Rheumatology
Risk analysis
Risk Factors
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Summary:Medication adherence is directly associated with health outcomes. Adherence has been reviewed extensively; however, most studies provide a narrow scope of the problem, covering a specific disease or treatment. This project's objective was to identify risk factors for non-adherence in the fields of rheumatology, oncology, and cardiology as well as potential interventions to improve adherence and their association with the risk factors. The project was developed in three phases and carried out by a Steering Committee made up of experts from the fields of rheumatology, oncology, cardiology, general medicine, and hospital and community pharmacy. In phase 1, a bibliographic review was performed, and the articles/reviews were classified according to the authors' level of confidence in the results and their clinical relevance. In phase 2, 20 risk factors for non-adherence were identified from these articles/reviews and agreed upon in Steering Committee meetings. In phase 3, potential interventions for improving adherence were also identified and agreed upon. The results obtained show that adherence is a dynamic concept that can change throughout the course of the disease, the treatments, and other factors. Educational interventions are the most studied ones and have the highest level of confidence in the authors' opinion. Information and education are essential to improve adherence in all patients.
ISSN:1660-4601
1661-7827
1660-4601
DOI:10.3390/ijerph191912036