Nasopharyngeal microbiome of COVID-19 patients revealed a distinct bacterial profile in deceased and recovered individuals

The bacterial co-infections in SARS-CoV-2 patients remained the least explored subject of clinical manifestations that may also determine the disease severity. Nasopharyngeal microbial community structure within SARS-CoV-2 infected patients could reveal interesting microbiome dynamics that may influ...

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Bibliographic Details
Published in:Microbial pathogenesis 2022-12, Vol.173 (Pt A), p.105829-105829, Article 105829
Main Authors: Kumar, Dinesh, Pandit, Ramesh, Sharma, Sonal, Raval, Janvi, Patel, Zarna, Joshi, Madhvi, Joshi, Chaitanya G.
Format: Article
Language:English
Subjects:
And SARS-CoV-2
Bacteria
COVID-19
Humans
Microbiota
Nasopharyngeal microbiome
Nasopharynx - microbiology
Opportunistic pathogens
SARS-CoV-2
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Summary:The bacterial co-infections in SARS-CoV-2 patients remained the least explored subject of clinical manifestations that may also determine the disease severity. Nasopharyngeal microbial community structure within SARS-CoV-2 infected patients could reveal interesting microbiome dynamics that may influence the disease outcomes. Here, in this research study, we analyzed distinct nasopharyngeal microbiome profile in the deceased (n = 48) and recovered (n = 29) COVID-19 patients and compared it with control SARS-CoV-2 negative individuals (control) (n = 33). The nasal microbiome composition of the three groups varies significantly (PERMANOVA, p-value
ISSN:0882-4010
1096-1208
DOI:10.1016/j.micpath.2022.105829